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Adverse reactions in patients in short-term fixed-dose studies were: nausea, dizziness, insomnia, hyperhidrosis, constipation, somnolence, decreased appetite, anxiety, and specific male sexual function disorders. That said, Pristiq is fairly new, and sometimes side effects surface after the clinical trials are finished, and the drug is being sold. It's very important, however, to keep in mind that all side effects are POTENTIAL side effects that more than likely will NOT occur. Hope this helps, Teri

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