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Thursday, June 12, 2008 abrenner, Community Member, asks

Q: Will Prestiq cause weight gain?

I am being put on Prestiq and am extremely afraid of weight gain.  Will this medication cause it?

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Answers (38)
Teri Robert, Health Guide
6/16/08 1:39am

The prescribing information lists weight loss as a potential side effect. Since it was just approved by the FDA a few months ago, there's not much history on it yet. Postmarketing data may show different potential side effects, but so far it doesn't look like weight gain is a significant issue.

 

Teri

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nnlb, Community Member
1/30/10 1:04pm

I was put on prestiq three months ago i have gained 25 lbs not sure its the prestiq or the advert i was placed on at the same time so i stopped both and i am miserable even gained 8  more pounds in the last tw weeks more emotional and depressed than ever in my life People speak to me and its like I have chronic PMs all I wanna do is cry lay in bed be hateful to my family and coworkers So today I will start back the prestiq and leave out the advert to see if i gain any more weight I just feel helpless

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crk, Community Member
3/ 7/10 12:45pm

You should never start two medications at the same time.  If one drug is unnecessary or interferes with the other, how do you know?  It's impossible to know what's causing what.  You have a dumb doctor.

 

I hope that the Prestiq on its own will help you feel better.  I've only been on it for a short time but already know that stop taking it results in a ferocious appetite and *gas*.

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k, Community Member
5/13/10 3:25pm

I don't know about the Prestique, but my friend lost 25 lbs. - however, I was very depressed like you sound and was taking Celexa and my doc boosted me a bit by adding Bupropion - and it definitely makes you not want to eat, and there is some nausea.  But I feel 100% better both physically and mentally.  Don't give up, the right answer is out there for you.

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Vonda Naff, Community Member
2/20/12 8:31pm

This is amazing!  I'm on 100mg of Prestique; along with Wellbutrin XL and Bupropion 15mg.  I've gained weight!  It seems like every med that says "no weight gain", I have the opposite!

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michaelle, Community Member
6/ 2/10 1:38pm

I was just YESTERDAY put on Pristiq and HOPE it will work for me. I just wanted you to know I am soooooo sorry about how you are feeling. I don't think enough people realize how EXTREMELY debilitating depression is!!!! I know how you feel!

Hang in there.... I will be praying for you!

MWink

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michaelle, Community Member
6/ 2/10 1:38pm

I was just YESTERDAY put on Pristiq and HOPE it will work for me. I just wanted you to know I am soooooo sorry about how you are feeling. I don't think enough people realize how EXTREMELY debilitating depression is!!!! I know how you feel!

Hang in there.... I will be praying for you!

MWink

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cinfdy, Community Member
6/ 4/11 10:27am

you need to get your thyroid and vitamin D levels checked

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RobertoRuiz Jr., Community Member
4/21/12 3:01pm

I was placed on prestique 4 to5 yrs ago I went from 225 to 310 but i later found out that it was the combination of seroquel that put on the wight i stopped the seroquel and still taking prestiqe dropped 50lbs in three mns and still dropping i am bi-polar adhd mild scitzo and great depp with suicidal tendencies taking prestique feel fine chnged to saphris for bipolar and anxiety med increased pretique to 100mg and still loosing weight xyprexa or ativan for anxiety seems to work for me with constant bloodwork to check your chemical imbalances now i am getting perfect scores 100percent so no prestique does not make me gain weight it was seroquel so find out what other meds might be causing your weight gain some people gain weight and eat more when deppresed watch what you eat health foods home cooked meals salads eat less but more than uased to will increase metabolism in body and weight will go down fast just you have consult your family doctor he seems to know all side effects and can help you with this weight gain so pray to God dont forget about Jesus as your Christ and savior and read your Bible learn to love God before anything and yourself and this will open your eyes to all your real blessings of Godly things and pull you out of your deppression do not stop meds without talking to your doctor if you feel better and slowly see how you 2 can work it out GOOD Luck and God Bless

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David in Oklahoma, Community Member
11/18/10 10:22am

Almost from the day I started taking Prestiq I have been gaining weight. A year ago May it was discovered my testosterone was at a very low level; around 132. It should have been in the 300's. With my first shot I started dropping weight without even trying and kept it off. I went from 204 to an average of around 164 to 168. I am still excersising 3 days a week. After 1 month on Prestiq I am up to 177 pounds. Prestiq is the only medicine I started at that time.

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glh, Community Member
8/ 5/11 2:49am

Things must have changed the last few years.  My doctor put me on prestiq and after going to my family doctor for rapid weight gain, I talked to my prescribing doctor and she read that it DOES cause weight gain.  I started out at 145 and I am now 207 and can not get it off. I am still on it, but not sure what else to take. It does work good, but at what cost? I am miserable at this weight.  I have always been a healthy eater and exercise all the time and this weight has made my mood worse. My doctor will not change it until I get my sleep pattern under control and then she we will work on it.  Mind you,i am a personal trainer and I cant train people to lose weight if I cant lose it myself. It DOES make you gain....

 

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Annette, Community Member
9/27/11 12:12pm

That is a real delima!  When my Dr. increased my dosage is when I noticed my appitite had decreased.  I went off Prestique to see if it was what was causing the EXTREAME persperation. Apparently it was the savella.  I will be starting the Prestique again and can't wait to feel good again!

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richvanc, Community Member
9/25/12 7:53pm

I'm on Zoloft + Quietiapine and I've gained huge amounts of weight! Do all SSRI's have this effect? Should I change meds.?

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elaine, Community Member
7/27/08 11:06am

I have been on Prestiq 50 mg for 9 days.  I have very little appetite,  so expect to lose weight rather than gain.

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nurse24, Community Member
7/12/09 11:53pm

I have been on prestiq for about a year. The first few week I had no appetite. But after that, I did experience weight gain..and I still am. I went from 125 to 140 :(

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Tabbi Rose, Community Member
3/ 6/10 11:30am

I have been on Prestiq for a couple of months (started at 50 and increased to 100 mg)and slowly the weight has been creeping up on me (15-20 pounds) but with so much going on, I somehow didnt notice until my clothes were really, really tight.  I have to go to work (my husband is unemployed) and now will have to purchase a new larger wardrobe which I can't afford.  I am going off this drug as soon as possible.  On top of the weight gain, I am still extremely depressed, inconsolable at times, crying at my office and at home all the time and overwhelmed by my life wishing I did not have to be here.

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nurse24, Community Member
3/ 6/10 7:40pm

aside from the weight, it sounds like this might not be the right medication for you. Talk to your doctor about it.

 

 

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naoma scott, Community Member
5/10/10 7:42pm

I have been on Prestique for six months and have lost nine pounds. I was told by my Doctor that this med. along with some other antidepressants do have this effect. I am now able to fasten jeans, slacks and skirts that were too tight before. Perhaps there is some other factor that causes weight gain in some people.

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fasme, Community Member
9/27/11 8:58pm

Hi Tabbi, I was on prestiq about 3 months ago and I stopped taking it.  I wasn't sure if that is what was causing me to gain weight or not.  I believe it was because of a nodel on my thyroid.  Since having it removed I have started loosing weight.  I am going back on the prestiq because I am not sleeping and starting to feel depress.  Please keep in mind that you need to talk to your doctor and let them know how you are feeling.  Especially if you are feeling that you wish you did not have to be here.  Maybe the prestiq is not for you.  There are other medication for depression out there that may work.  The one thing about medicine is that it works differently on everybody.  One person may gain weight and the other one may loose.  This is why it is very important to talk with your doctor about any concerns that you may have regarding the medicine that they are prescribing for you and make sure that you talk to the pharmacist because they know more about the medicine than the Doctor's does.  I wish you the best and pray that you find the right medicine that will help you.  It can be over whelming when a person looses a job and you have to reenter the employment field and are suffer with depression.  Barbara

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Lisa, Community Member
7/19/09 12:28pm

I just started taking Prestiq on Thursday and I'm hoping it works as well as I'm hearing it does.  I had to go off the Abilify for medical reasons and that put weight on me like 2 sizes up. Horrible. But the Abiligy really worked.  I hope the Prestiq works just as well with out the weight gain.

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Bobbijo, Community Member
1/ 5/10 6:14am

I have been on it a month and lost weight. I can hear my heart beat in my ears...Has that haappened to you too?

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molly, Community Member
2/26/10 7:27pm

 my dr. just put me on  prestiq and it made me  jittery and made my heart beat fast . was on zoloft . should i discontinue and go back on zoloft?  and let my dr. know.   thanks!!

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jgh, Community Member
6/ 4/10 4:16pm

my doctor told me that it can cause an increase in blood pressure.  if you have blood pressure issues, you may need that adjusted.  i hate that in order to help one problem (depression) - it seems to set off a chain reaction of others (blood pressure, weight gain, etc.)!  hang in there.

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Shirley, Community Member
2/15/11 7:49am

This sounds just like me except I stay hungry and thirsty and I guess I could just sit and eat in bathroom because whatever I eat sends me there. I think with the weight loss its because nothing last in my stomach. I have not felt good for two weeks and thats how long I been on it. I have never been a person to have gas and now I am a walking gas machine shame I can't bottle it. I have heard many good things about this medication but I have yet to see and thing positive for me to even stay on it. Oh and I have never had high blood pressure now my blood pressure is boderline and sometimes high I am 56 year old

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Amy, Community Member
8/ 5/08 6:08pm

Due to the fact that Prestiq has two ways of working in the brain SNRI it will help with your anxiety as well as depression and most people have both whether they realize it or not.  People who are depressed and anxious without medication will try to cope by either emotionally feeding their depression or become somewhat anorexic in their acute state.  Once people start feeling the effect of the chemicals in their brain they will feel the medication working and experience side effects like being dizzy or feeling flu like symptoms...and may not have an appitite.  I've been on a form of Prestiq for 6 months and I know if I skip a dose because I start to feel like I'm just discovering I'm pregnant-sick to my stomach, dizzy and a little out of it.  Then I run for my meds!  I feel much more calm and depression isn't an issue.  Anorgasmia comes into play unfortunately with all antidepressants and adding Wellbutrin cost more and had NO effect at all.   I actually lost 10lbs on Effexor XR and kept it off.  Never stop taking any drug that changes or alters the chemicals in your brain.  It's a tapering off that will prevent any serious sudden side effects.  Would you ever abruptly stop taking a drug that effected your heart?  No so think about how stupid it would be to shut off the chemicals to your brain like a faucet...don't be stupid and blame it on the medication like so many of my friends have done.  You'll experience Seritonin syndrome.  Google it.  Here's to feeling in control again and whatever brought on the depression and anxiety...may not go away or change but now you are better 'equipped' to handle it.  ***one important thing too is a lot of times Antidepressants will be stimulating and cause you to have difficulty falling asleep...change it to the nights and ask for a temporary sleep aide.  The side effects definately taper off after a few weeks.    

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Lynna, Community Member
8/22/08 1:13pm

I have been on a number of anti-depressants and they usually do cause me to gain weight. However, I have been on Prestiq for a couple of months and I have lost weight w/o any change in my eating or exercise patterns so at this point I believe it could be caused my the Prestiq.

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dyangre, Community Member
8/25/08 7:29pm

I recently changed to prestiq from celexa and so far if anything, it has cut my appetite. Since I have had a gastic bypass, I will just need to take a multi-vitamin and make sure I am eating a good diet.

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Jim, Community Member
8/28/09 9:00pm

I would love to hear more from who ever wrote the response related to changing from Celexa to Prestiq. I am curious to know how long you were on Celexa, why you changed. I have a friend who is preparing for this same change; and its because the Celexa does not appear to be working, 14 weeks. Was there much of an adjustment to the new medicine. Did you experience any withdrawal from  going off Celexa?? How do these medicines differ in how they treat your depresion. 

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Tawania, Community Member
1/21/10 10:05pm

I am currently switching from Celexa to Prestique also.  Celexa was having a negative effect on me.  It worked really well at first but the longer I was on it...the worst my symptoms became....aggitation, irritability.....exhaustion....just to name a few.  With increased dosage....I was having nightmares, loss of sleep....severe irritability!  I have heard only positive about Prestique....looking forward to the change.

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Tawania, Community Member
1/21/10 10:10pm

sry.....*Prestiq*

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Melissa W, Community Member
5/ 4/10 10:19pm

I am also switching from celexa to Pristiq.  The reason I asked for the switch is because I was losing a lot of hair from Celexa.  Apparently it's really rare, but some women on Celexa do experience alopecia.  So, it's only my first day on pristiq, but I haven't had much of an appetite today, although I did have a little trouble sleeping though, but I've always had an issue sleeping.  I'm looking forward to my hair not falling out as much though!!  

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Dawn Bourgeois, Community Member
10/ 2/10 1:32am

I was on Lexapro, then switched to Celexa, and had no weight gain from either, after getting off of the Celexa for a few months, all of my anxiety, aggitation and irritability came back, I've been on Prestiq for 3 days now and felt a magor difference the first day, but I have no appetite what so ever, just making sure what I do eat is nutritious, and taking multi vitamins, so far lost 3 lbs. I find that after 12 hours I do become somewhat sleepy. I works great for me.

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MaMa_A, Community Member
9/ 6/08 10:01pm

I started taking Prestiq for migraines, not depression.  Since I started taking it, I have easily gained a pound a week (and I am not one to gain weight easily).  So now I truly am depressed, and hoping that the Presiq helps with that.  I have no clothes that fit, and I feel bloated and plain horrible.

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elibella, Community Member
9/14/08 9:22am

I have been on prestiq for 1 week and notice a slight decrease in appetite due to the fact that I have difficulty swallowing at times.  I do wake up at night a few times, but I am told that will go away.  It is helping the depression and anxiety for sure.  I feel more calm and able to control my emotions. 

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C Britt, Community Member
11/23/08 10:40am

I was put on celexa 20 mg. in June. It worked just fine; but I gained 8 pounds in 5 mos. I lost a great deal of weight  5 years ago and have watched my diet closely since then. Believe me, I was not eating more. My doctor just changed me to prestiq last Monday and I have already lost a pound and I feel more alert. The celexa sort of wore off by dinner time and I was ready to crash. I have moderate depression, anxiety and panic attack. I am just glad there are some drugs out there to help because I was so depressed over my husband's terminal condition and being his caregiver for 8 years I was about to give up myself. So far, so good with prestiq.

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ttoe755, Community Member
1/ 7/09 11:34pm

I have been on presiq for about a mth. I have noticed i have very little appetite, and when I am hungry I get full faster than before.. So far so good. This was one of the reasons my doctor prescribed this medicine for me. I was so afraid of gaining weight that I had put off antidepressants for about a year.

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kim, Community Member
1/20/09 7:16pm

I was on lexapro for 6 months and ended up gaining a whole 17 pounds from it. I model so naturally I eat healthy and work out everyday, so clearly it was the medication that made me gain the weight.  I have done everything in my power to make the weight come off and it has yet to do so.  My doctor was so concerned with my excessive weight gain that he switched my medication to prestiq.  It's been sitting in my closet for 3 months now because I've been so afraid that another medication I take will cause even more of a weight gain. After reading people's answers to this question and suffering horribly from anxiety I have finally decided to try out prestiq.

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Candace, Community Member
2/ 5/09 8:53pm

This is my first week on it and I already lost 5lbs after 7days and I feel great!!!

Lexapro made me gain 15lbs.

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reesie1825, Community Member
2/17/09 8:48am

I just started taking it too. Everything I have heard so far actually states the opposite. It's more likely to cause lack of appetite as opposed to the lexapro I was on previously (50 lb weight gain over 2 years)

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cjohnson, Community Member
4/ 1/09 10:34am

When I first started on Prestiq I did lose weight due to no appetite, etc.  I have been on it now for 1 year and I have gained 10 pounds.  I have maintained my exercise schedule and feel that it is due to the medicine.  I am going in for my one year check up and plan on asking her about this.

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Leesuh, Community Member
6/ 2/09 6:23pm

My Dr specifically put me on Prestiq because I have been losing weight (her orders!)

and she said this would not hinder that weight loss Smile

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Leesuh, Community Member
6/ 2/09 6:23pm

My Dr specifically put me on Prestiq because I have been losing weight (her orders!)

and she said this would not hinder that weight loss Smile

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Al, Community Member
6/11/09 7:13pm

I have been taking Celexa for a little over a year.  My doctor is reducing it to begin Prestiq.  Is anyone else taking a combination?  How did this effect the weight gain or loss?

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Becca, Community Member
6/22/09 1:35pm

I have tried so many different antidepressants and prestique has been the best ever.  I started taking it about 2 months prior to my historectomy and because of it I lost 17 pounds with in a month of my historectomy and my kids and husband love me because the mood swings are at a very low minimal.  The other thing I like about prestique is it doesn't decrease your sex drive.  I am in my early 30's and at my sexual high.  If anything else it greatly increased it.  So now I feel good, my kids are happy and my husband is VERY happy.  I would suggest to anyone needing something for their nerves and drepression to ask their doctor about it.  I don't even have to take hormone pills because of it.  It's wonderful...best anti-depression med out there!!!!

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angela, Community Member
10/10/09 1:02pm

thanks for the info. i start taking prestiq in 2 days.

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kee, Community Member
1/ 3/10 10:08am

i have been on celexa and trazedone for about 3 years.  when i increased the dosage i gained more weight and felt totally numb.  i would like to try prestiq but am worried about the nausea.  when i took lexapro i felt like i had morning sickness. it was hard to even work with that nausea.  also, can you drink while taking prestiq?

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Coolcat, Community Member
1/11/10 10:42pm

I am on Pretiq for abt a year, at least.  It has few side effects for me, actually helped me sleep better than before but I still do have sleep problems but they were worse before Prestiq.  I do still get anxiety and take meds if I really feel totally stressed and anxious, was prescribed them daily (Klonopin 3 X a day) but I do not take them often.

I felt slightly nauseaus when I started prestiq but I noted that if I eat FIRST then take the meds I am not nauseaus.  I hoped I would lose weight but have gained all that I had lost when I was so depressed and sad that I could not eat at all for 3 months I lost 23 pounds and have gained it all back  because I feel hungry all the time and never feel full.  I had that issue before on Prozac too.  And the worst was LExapro, felt carb cravings really bad. I could not handle Welbutrin, wished I could because I want to lose weight and cannot no matter how I cut back and exercise (but I do have very high cortisol - a stress hormone, so I put a lot down to that.  I am on 100mg of Prestiq but I understand most people take 50 mg only.  I have a history of depression for at least the past close to 30 years. 

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slammr, Community Member
5/ 5/10 11:20am

I automatically started prestiq at 100mg and i'm only 4 ' 10 1/2" and gained 15 pounds.  I have been on so many  antidepressants that have made me gain weight also and am at my wits end.  Prestiq works almost to its best for me but the weight gain then makes me more depressed.  I know Prestiq is supposed to not make you gain weight but for me it's the opposite.  Is there ANY antidepressant out there, old or new that won't make me gain weight that you know of?  Thanks for the input.

 

Cheryl

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STAR, Community Member
5/ 5/10 1:50pm

I know exactly what you are saying.  I'M 5' TALL, adv. weight bout 105,  now after 3 mths of PRESTIQ I'm up to 120.  I take it along wit 40mg paxil. maybe thecombo of the 2 is makeing me fat;, depressed, hungry, gasssssy, u name it.  rt now I hate myself.  absolutely, nothing in my closet fits.   gonna call my DR. TODAY. IF YOU FIND AN ANTIDEPRESSANT THAT DOESNT MAKE YOU GAIN WEIGHT PLZ LET ME KNOW......

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slammr, Community Member
5/ 6/10 11:21am

I will let you know if I find one.  It's hard to find one.  Paxil made me gain weight too.

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dg, Community Member
8/ 8/11 3:21pm

The only thing that does not cause weight gain is Wellbutrin.  That will actually rev you up, rev up your sex drive and help lose weight.  Unfortunately that is not enough for me.  I have gone from 120 to 145lbs..5' 2".  I hate it.  I was put on prestiq a month ago.  I ache all over and am sleepy as well as jittery.  Don't know if I will continue this.  I have tried everything else, but always have no sex drive or ability to perform..Anyone else have trouble with this?  EVERYTHING affects me this way except Wellbutrin.  I have tried, zoloft, celexa, prozac, paxil, effexor, cymbalta, remeron, lexapro..whatever..they all kill the sex life.  Ugh!

 

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Misty, Community Member
3/19/10 3:04pm

I am so glad to hear how well this is working for you...I have tried many anti-depressants and nothing has worked for me...If they didnt make me sick they threw me into a panic attack....Im suppose to start Prestiq tomorrow.I hope it works for me...Thank you for sharing your success!

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Syndee, Community Member
7/ 8/11 5:53pm

Wow..thats good to hear! Glad it is working for you. I had a hysterectomy about a year ago and I am in my 30's.I have been on Celexa for mood swings and have gained about 20 lbs. The Celexa doesnt seem to help and I have lost my sex drive completely and have been experiencing anxiety attacks lately. My doctor switched me to Prestiq today. Hope to get good results.

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carla, Community Member
8/25/09 1:34pm

Has prestiq increased or decreased sex drive and the ability to orgasm?

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lkehres0519, Community Member
9/16/09 1:25pm

I have been on prestiq for about 3mos now.  I went from 138lbs to 125! I had no idea why I was losing weight until I read all the posts regarding other people losing also.  I was nervous about gaining weight too and decrease in sex drive.  Can honestly say this is the first anti-depressent I have taken that caused me to LOSE weight and did not decrease my sex drive. 

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Lynn, Community Member
10/14/09 12:29am

I was taking Cymbalta and due to added stress from being given someone else's prescription at the pharmacy, and taking it, I went into a deep depression. I was having panic attacks, had to change pharmacies, but still was very depressed. I was actually diagnosed with clinical depression. My doctor added Prestiq in addition to my Cymbalta. I have been on both anti-depressants for about 3 months now. Within 2 weeks my deep depression lifted and I felt normal for the first time in several years. As far as weight gain, I experienced no appetite whatsoever. In fact I had to make myself eat because I was never hungry. Due to a knee replacement, I gained 50lbs. Since taking Prestiq I have actually lost over 20lbs in 3 months. I still have no appetite and have to ensure that I eat properly since I am hypoglycemic. Personally I would recommend Prestiq to anyone with severe depression, without fear of gaining weight. I have been on many anti-depressants over the years that I had to stop because of the side effects but with Cymbalta and Prestiq I do not have any noticable side effects. I feel normal and back to my old self and could not be happier with the results.

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Jan, Community Member
12/28/09 4:42pm

I have been on Prestiq and Seroquel for 5 mths --- yes, I have gained weight. My waist is now a Costco Muffin Top, and my boobs are large. I was a "loose" size 10 and now I am a tight and bulgin 12 (should be 14 - but pride...)  My moods and my crying episodes have calmed down, and I sleep about 3-4 hrs a night now compared to 30 minutes every now and then.  It's worth the pounds.

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Jody, Community Member
3/ 4/11 9:47pm

Its the Seroquel! Trust me on this. I was put on TONS of anti-depressants with seroquel....Seroquel not only makes you gain weight...with weight gain comes diabetes...etc. The doc...ended up taking me off all anti depressants and had me taking a lovely cocktail of Adderall and Seroquel. I LOST tons of weight because of the adderall, but I wasnt human...I didnt feel grounded!. I decided to get off all meds and see a different doc. He has put me on Prestiq and im hoping this helps. Lexapro, cymbalta, zoloft, well boutrin, celeza, paxil....NEVER WORKED! I am also taking xanax for my panic attacks...WORKS GREAT. Please consider talking with your doctor about Seroquel...Its a really BAD drug. It shouldnt even be allowed on the market!!

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slammr, Community Member
4/29/11 12:08pm

why was Seroquel so bad?  At one point I was point on it but I got side affects and was taken off.  I am more concerned the gaining weight. I am taking Prestique 100mg now and have gained 30 pounds (but had a previous problem before that) but my dr. wanted to add that to what I am taking and just concerned about the weight gain.  Can you tell me what you?

 

Thanks

 

Slammr

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lisa, Community Member
1/11/10 2:19pm

at first, I lost a little weight,but in the end I definitely gained

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Jim, Community Member
1/22/10 8:53am

My client, female in her 40's, was changed from Celexa to Prestiq and the Prestiq is prescribed at 100mg. She has been on this for four months. There have been no major side effects. Once in a while she gets some gastro upset, but this has been controlled with Prilosec/Omeprazole. No weight gain. No sexual side effects. This drug works more with Serotonin and Norepinephrine; and the latter has really increased energy. Now the work is getting the cognitive/emotional part to match the physical energy. My own research with Prestiq seemed to reveal it would be easier to transition to Effexor from Prestiq as opposed to Effexor to Prestiq. So far this has been a good medication for her depression. Good luck to all those who struggle with this mood problem.

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canadienchick_2003, Community Member
1/22/10 2:27pm

I am currently on Efexor and i dont find it is working for me. I was on 75 mg 2 x a day then my doc put it to 75 + 37.5 2 x a day and my anxiety got worst. I have an apt to go see him on Monday and was thinking if asking to be changed to Prestiq. I was just wondering what you have revealed about the changing from effexor to prestiq?

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Jim, Community Member
1/23/10 6:42pm

I read that changing from Effexor to Prestiq can be difficult. Some people complain they get too many side effects from the withdraw. Nausea, more depression, etc. Seems going from Prestiq to Effexor would be better. Effexor XR is better than Effexor. With your depression, if you have problems with energy, physical motivation, lethargy, you may like Prestiq better, especially at 100mg. Start at 50 then go to 100, maybe after 2 weeks. You might want to consider a slow with draw from the Effexor 225 to 150 to 75 to 37.5. The doctor will need to supervise the plan. My clients have done pretty good with Prestiq 100mg in the morning and Klonopin (anti-anxiety) two a day  and one at night, .50mg . Some people don't get side effects from dropping a medication. If you don't, you could transition to Prestiq quicker. I wish you best of luck. Depression is difficult to treat. Therapy along with the medicine helps. Do more research on these medicines so that you are ready to discuss medication plans with the doctor. Sometimes doctors want to augment antidepressant medicne with antipsychotic medicine like Seroquel, Abilify, Risperdal. Be careful with these. Some cause problems with sleep and some heavily sedate. THere are other medicines like Effexor and Prestiq. Cymbalta, Wellbutrin (these are SNRI meds) Prozac, Paxil, Celexa, Zoloft are SSRI. SNRI deal with Serotonin and Norepinephrine (more for those needing energy); SSRI work with Serotonin.  Read, research and don't give up. You will find a medicine that works. My client has relatively few side effects from the Prestiq.

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jax1234, Community Member
3/28/10 6:02pm

I am currently taking wellbutrin and I am still feeling depressed. I am also a very anxious person, my doctor  recommended possibly adding another antidepressant at a low dosage like zoloft or prestiq, One of my biggest fears is weight gain. I have tried zoloft, effexor and paxil and they alll made me gain over 30lbs.  Any suggestions???

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Jim, Community Member
3/30/10 9:30am

Most clients in our office have gained a great deal of weight from most of the antidepressants and antipsychotic medications. The one SNRI that has been used with fewest side effects is Pristiq at either 50mg or 100mg am. Wellbutrin treats only depression and has little effect on anxiety. Pristiq linked with Klonopin .50mg 2-3 times a day helps control anxiety and depression. One needs to be careful with Klonopin, Xanax, Ativan due to the addictive potential. But the Klonopin is the best of the three. Ativan is better for emergency. Your doctor wants to add an antidepressant Zoloft (SSRI) there is weight gain from it like there is with Paxil, Prozac, and others. If the doctor wants to augment the Wellbutrin, you may want to consider Pristiq. But discuss interaction of all your medications before agreeing to take anything. Talk to a pharmacist about Wellbutrin, Pristiq, Cymbalta, Effexor XR, Zoloft then I think you will be more able to have a conversation about your medicine.

 

Exercise, slow up on carbohydrates, walk everyday, drink more water, explore other medicines that can help with weight loss. Get familiar with Dr. Mirkin's medical reports that may have other suggestions about diet and weight loss. Good luck.

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slammr, Community Member
2/ 3/10 10:47am

I have been on Prestiq for about 2 1/2 months now and are having a bowel problem.  Was wondering if anyone's stool has changed color from regular to an orangey color.

 

Thanks.

 

Cheryl

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Melissa W, Community Member
5/ 4/10 10:26pm

Not sure if this helps, but I did read that the capsule does not get digested by the body and can show up in stool.  Perhaps this is a partial cause??

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dianaboyd, Community Member
4/28/11 2:01pm

it is making me constipated just started it 2 weeeks ago but my other concern is the price 160.00 WOW what price happiness well not even happy but really it is so sad that you gan't even try to feel better the money causes stress does anyone no of coupons or whatever                    thanks Diana

 

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blueslady07, Community Member
4/18/10 3:58am

No weight gain!  In fact, I have lost about 35 pounds with diet and exercise over the past 8 months.  After having had gastric bypass surgery, the last thing that I wanted to gain back any weight, and I am probably the only one who has gone to the weekly meetings of the big weight loss

 

Let me begin by saying, that my doctors were concerned about trying me on Prestiq because it is not recommended for bipolar and it can throw you into a manic episode if you are bipolar, but with me they were running out of options because I have been on just about everything else on the market, and had terrible side effects with most of the SSRI's that I have tried and some of the others (bladder incontinence)   Prestiq worked so well for me with 3 hours of taking my first dose, I felt "normal" and I had not felt that way in 30 years, and it did not make me manic. 

Since I have been on Prestiq I have lost about 35 pounds in about 8 months.  Of course, I have been trying to lose weight, dieting and exercise on top of that.  But Prestiq is the first anti-depressant that I have been on that has given me the energy to get up and do any type of exercise.  After having gastric bypass the last thing I wanted to get back on something and gain back any of my weight!  The only side effects I have had from the Prestiq are very slight nausea about an hour or so after I take it in the morning but that only lasts about 15 or 20 minutes, and a trouble going to sleep so I take it in the morning and that problem is solved.  I have been taking antidepressants, etc for bipolar for about 30 years, and Prestiq has worked better for me than anything I have ever been on.  I had been on some other antidepressants and I could exercise for what seemed like an eternity and watch what I ate, and still gain weight, but not with Prestiq. 

 

My doctors were concerned about trying me on Prestiq because it is not recommended for bipolar and it can throw you into a manic episode if you are bipolar, but with me they were running out of options because I have been on just about everything else on the market, and had terrible side effects with some of the others (bladder incontinence)   Prestiq worked so well for me with 3 hours of taking my first dose, I felt "normal" and I had not felt that way in 30 years, and it did not make me manic. 

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SPierce, Community Member
7/ 2/10 11:47am

I do not know if it cause my weight gain but I do know that I gained over 20lbs while taking.

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John Martinez, Community Member
8/16/10 5:20pm

I've been on Prestiq for about 2 years and and on antidepressants for about 9 years in total.  in those 9 years i've gained a total of 100 lbs.  I can easily blame these drugs since I've always been a slim guy all my life.  But then I had to factor in the fact that I was 33 when I developed this condition and I'm 42 now. I never exercised and I almost always over ate.  So it's hard for me to blame Prestiq or one of the other many drugs I've been on.  I think if we all just admit that we really don't exercise like we should then we can stop blaming Prestiq for our own failures.  I take Prestiq and it has helped me so much.  I hope one day to be off of all drugs completely.

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Michele, Community Member
5/15/11 6:21pm

Yes, I lost a hundred pounds 2 years ago and have kept it off.  I got mono in Nov and was depressed and the doctor put me on prestiq.  I was not eating much because I was sick and I gained 30 pounds in 2 months even after the mono. I didnt like the drug at all.  I am now I wellbutrin.  Stopped smoking, have energy and I lost my weight.  I take 150mg 2x a day.  Prestiq is so new and I felt the drug companies are pushing it.  Hope this helps! :)

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Debra Lowenstein, Community Member
8/29/11 7:30pm

Yes it will and most likely cause weight gain and in time lose you sence of taste as I did and it will never come back, The manufactorers of this product have no idea how to come off of Prestiq or that it causes taste buds to die off.

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franny, Community Member
9/ 9/11 4:38pm

i started prestiq 3weeks ago and lost 8lbs best of all i lost more in inches i think it depends on the person. what might work for me maybe wont work for you.

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Annette, Community Member
9/27/11 12:00pm

I have been on Prestique for about 9 months.  It decreases my appitite making it easy to loose unwanted weight.

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Upset, Community Member
10/10/11 9:00pm
The ifo sheet states weight loss but I have gained weight and my doctor Told me most of his patients on this med were having the same complaint Of gaining weight and fast Reply
karinann, Community Member
2/ 2/12 6:29pm

I was put on prestiq about a yr ago. I lost weight in the first few months but have never gained..

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karinann, Community Member
2/ 2/12 6:30pm

i have been on prestiq for a year. I lost weight and never gained

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candy, Community Member
2/24/12 1:02pm

ive been on pristique for a few yrs and havent gained weight, but i do know if you dont feel hungry eat anyway, cause not eating will cause you to gain weight really quick cause your body holds it in cause your not eatin enoough...  so eat even if your not hungry girls! lol... and the weight will stay off.. good luck to all! :)

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candy, Community Member
2/24/12 1:02pm

ive been on pristique for a few yrs and havent gained weight, but i do know if you dont feel hungry eat anyway, cause not eating will cause you to gain weight really quick cause your body holds it in cause your not eatin enoough...  so eat even if your not hungry girls! lol... and the weight will stay off.. good luck to all! :)

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rufus, Community Member
6/25/12 3:18pm

I have been on Prestiq since it first came out to use. I also have been on seroquel for many,many years.Prestiq made me gain and seroquel made me gain. BUT I feel great and am happy. My side effects have been the weight gain from 154 to 262lbs. From size 10 to now 3x women's clothing.  My head sweating is another side effect that makes my hair wet and drips down my face--it can be embarassing, and dry mouth which is commonand because of dry mouth my dentist says I get cavities under my crowns which is expensive to get new crowns every 2 or 3 years.

I have been depressed for some 25 -30 years.Tried many,many other depressive meds. Even though I hate the weight gain,

I like that I feel normal,happy and can function so well. I don't want to give up this "good feeling"  For years I would be very irritable and very emotional cry at the dumbest things, even sad things on news or in movies would cry where others would just say oh that is sad.

So for me I hate being sooooo fat but I like feeling good. So I hope they invent through research a new antidepressive that doesn't make just huge weight gains.

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rufus, Community Member
6/25/12 4:43pm

I just talked with my psychiatrist as my medical plan will not pay for Prestiq anymore as it is too expensive. I was paying a co-payment of $90. for it.

The medical plan suggested venlafaxine HCL XR which would only be $7. co-pay.

So he changed it to that. The doctor also told me that Prestiq changes in the body to venlafaxine anyway which is also known as Effexor XR. He said venlafaxineHCL will just go through the body like water so won't be in your system long enough to help. So always ask for venlafaxine HCL XR which slowly goes through the body.

 I used to be on effexlor XR before prestique so should have stayed on it and would have saved a lot of co payments.

    I also have really bad head,hair and face sweating so he said to

take prescription Hytrin 1 mg and it should stop the sweating. I hope it works as the wet head from sweating was very embarassing. It is really a high blood pressure medicine. I don't have high blood pressure. But it also works on sweating.

He said to get a thyroid panel blood test. To see if that might be the weight gain as I am now obese.

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By abrenner, Community Member— Last Modified: 03/12/14, First Published: 06/12/08