I would love to hear more from who ever wrote the response related to changing from Celexa to Prestiq. I am curious to know how long you were on Celexa, why you changed. I have a friend who is preparing for this same change; and its because the Celexa does not appear to be working, 14 weeks. Was there much of an adjustment to the new medicine. Did you experience any withdrawal from going off Celexa?? How do these medicines differ in how they treat your depresion.