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I don't know about the Prestique, but my friend lost 25 lbs. - however, I was very depressed like you sound and was taking Celexa and my doc boosted me a bit by adding Bupropion - and it definitely makes you not want to eat, and there is some nausea. But I feel 100% better both physically and mentally. Don't give up, the right answer is out there for you.

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