Hi, there.  I'm sure the doctor prescribed whatever he/she thought was the best combination of medication for your mom.  She might be quite sleepy, at least for a while, as two of those drugs, at least, have a sedating effect.  Was your mother in the hospital, or has she had depression for a long time?  Everyone's different in how they react to treatment and the Lexapro may not "kick in" right away if she just started taking it.  As long as she keeps in touch with her doctor and tells him/her if anything isn't right, she should be okay.  The best thing you can do is let her know you are there for her.  Good luck, I hope she's feeling better soon.