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Saturday, October 09, 2010 JIll asks

Q: Wellbutrin given to counter act Celexa

I have recently been prescribed celexa by my doctor.  I noticed that I was less "in the mood" than I was before for sexual activity.  My doctor then gave me wellbutrin and said if I take it before I want to be sexually active it will negate the effects of the celexa and hopefully allow me to get in the mood.  Now i've read things stating that they work together as anti-depressents and nothing about one counter acting the other.  What should I beleive??

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Answers (1)
John Folk-Williams, Health Guide
10/ 9/10 3:43pm

Hi, Jill -

 

I'm no doctor but someone who's dealt with depression over many years. I do know that celexa and wellbutrin are often prescribed together when celexa alone isn't doing the job - putting them together is said to be more effective than switching to wellbutrin from celexa. The combination works a lot better for many people (didn't help me, though).

 

Wellbutrin works on two neurotransmitters that celexa doesn't affect. One of those is dopamine, linked to pleasurable feelings. Studies report that many taking this combination experience a higher level of energy generally and also improved sexual interest.

 

That only happens, however, when you take both together every day. I've never heard of taking wellbutrin beforehand helps immedately with sexual activity. The antidepressants have to build up to a certain level in the blood before they work at all. I've just never heard of this way of taking it.

 

Always ask you doctor if you have any question. Antidepressants have powerful effects, so it's also good to get a second opinion from a psychiatrist.

 

John

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10/10/10 3:38pm

Thank you very much for the advice

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By JIll— Last Modified: 12/27/10, First Published: 10/09/10