• angelastover25 angelastover25
    October 15, 2008
    Does prozac cause joint pain?
    angelastover25 angelastover25
    October 15, 2008

    I have pain that has started over the past few days.  It satrted in my left hand and wrist.  The following day it started in my left knee.  Then one day later, it had moved to my right hand, also.  I'm waiting to see what happens next.  The pain is almost unbearable.  It hurts to move any of them.  I'm not sure what's going on.



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  • Lisa July 01, 2010
    July 01, 2010

    In the 90's I took prozac (Fen Fen combo) with lack of feeling anything as a result.   Several years later as a result of depression I was put back on Prozac by my doctor.  Within days I started with severe pain beginning in my distal joints (fingers, toes).  Within 3 days it had worked it's way into my elbows and knees so severe that I could not even walk or move.  I literally thought I was dying as nothing counteracted the pain.  The addition of prozac was the only thing that had changed in recent days. I stopped the med and within 3 days the point slowly went out of my joints. After the death of my husband a few years later, I thought I would give it a try again with severe joint pain beginning again in the same manner.  I immediately stopped the drug and now list it as a drug sensitivity.  It is an uncommon side effect that is rarely noticed in the side effects.

  • lifeiznuts October 17, 2008
    October 17, 2008

    I'm glad you asked this because I've been having joint pains for some time, among other things.  Up until this moment, I was on the "Prozac-for-life-plan."  That's my way of putting it.  But now I'm wondering if that's really a good thing.


    I did a Google search on "Prozac joint pain" and found this: 




    The list of side effects will blow your mind.  Joint pain is among them.  When I started on it, all of those side effects were not listed.


    Welllllll, I think I'll make an appointment with my shrink for next week!

    • jag7272
      May 05, 2016
      May 05, 2016
      I also was on the "Prozac for life" plan and suffer from severe arthritis. I recently decided to try to cut back on my dosage because, as I get older, I find myself taking more and more everyday prescription drugs simply because I've been taking them for so long. My joint pain is significantly less since I cut out Prozac completely. I can't help but wonder if all the pain I have suffered could have been eliminated by just stopping Prozac!!! READ MORE
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  • RAYVIC17 October 17, 2008
    October 17, 2008

    Hi Angela,

      It doesn't really matter at this point whether or not it is the Prozac that is causing your pain. Call your doctor now and tell all - whether you get the answering machine, the secretary, or doctor, tell the entire problem - all your pain, etc and ask for immediate advice...........you are the person with the pain...take control! Don't suffer any more.

      If it's the meds, there are many more to choose from. You may have some other problem that should be checked right away. Do it now!! Don't be afraid.

    Take care,....good luck with it.

    Ray Malin M Ed

  • MsDolly October 26, 2013
    October 26, 2013

    I have been on 20 mg of Prozac for about three years now.  The aches and pains have been a fact of life for me during the course of these years.  About 4 months ago I asked for my meds to be doubled as I was dealing with my mom's deteriorating health and eventual death.  I immediately started having worsening symptoms.  My feet, ankles, hips and spine were always paining.  I went to my doctor and she sent me out for X-rays.  The results came back and I was told that my body was full of mild to moderate Osteo-arthritis.  Day by day my condition was getting more serious. One day while perusing the internet I came across a site that was discussing the ill effects of Prozac.  Everything became very clear to me at that moment.  The Prozac was the culprit of my pain.  Prozac contains Flourine and from what I have read it can cause Skeletal Fluorosis which is often mistaken for Osteo-Arthritis.  I immediately went off my Prozac medications and my aches and pains have been subsiding day by day.  Do a little research and find out for yourself.

  • starrshine33 March 26, 2009
    March 26, 2009

    Interesting...I was put on a low dose of Prozac to REDUCE my joint/muscle pain...  I've been having "growing pains" since I was a child...and they can't figure out wha'ts wrong with me...recently the doctor prescribed Prozac because he says it can help with the pain...I think he just thinks I'm nutso.... :)

  • graham7402 October 19, 2008
    October 19, 2008

    I don't know if this is a fact - but I have been on prozac for several years.  I have severe joint pain and have thought I have early age arthritis.  I guess it makes sense that it is from prozac as I didn't have this problem prior to it.

  • aanthonysavone November 09, 2015
    November 09, 2015
    Same problems; recently through the past week I've been getting severe muscle stiffness but I've been up the dosage of prozac; It started one night when I invited my friends over to watch baseball then swim, then when swimming comes I feel like a small compression turn into a massive unexpected and unexplainable pain in my left foot then to see my big toe all the way to the left and all other toe pointing down and far by far meaning looking as if dislocated. Then next night my friends keep joking about it then around 15 into playing video games I feel my inner right thigh feel an even more probably as if It was getting smash pain that lasted for a minute or two even then instantly went away. Two day go by then start to feel it build up, then a hour later to get pain In both legs and arms to just be frozen in pain and out of breath just to my friends laughing as if a joke. Okay this was last week, Saturday 11-7-15 and Sunday 11-8-15 I was at multiple friends houses to hang out to feel my body for 1 hour each day for three times around 3am 7am and the worse 1pm; as type this my left foot is in pain for about 5 minutes and is stiff and can't move. I'm Anthony with a problem as others and would seek for help at slimacts82@aol.com READ MORE
  • Jt
    June 18, 2014
    June 18, 2014
    I was on another type of antidpressant called cymbalta and after about four months I was diagnosed with severe carpal tunnel. Now I'm on prozac and I've been on a low dose of 10 ml and now I'm starting to feel pains in my wrists and knees. READ MORE
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