Hi Gray

You ask a very poignant question.

I assume you mean, "Will my depression ever end?"

Here are my thoughts...as long as you are a human being...you will have life challenges and times in your life when you feel sad. 

But depression is a different matter and I can say...yes this can end.  The extreme feelings of despair do lessen.  I cannot speak for anyone else to say that your biological predisposition to having depression will end.  I feel I have had my depression all my life...but there are tools which everyone can put in their arsenal to feel happy again.

I have always liked the saying, "This too shall pass" when I fall to the bottom of my depression well because I do know...historically...that my depression does life at some point whether it be due to changes I enact or just naturally.

I think you need a bit of hope so I will give it to you now.  It is possible for you to feel better. 

Hang in there.  Let us know how you are doing.