Hi Stephanie,

I looked up the information for Zoloft in the Physicians' Desk Reference because I knew that the maximum dose for Zoloft is 200mg daily, but I wanted to see it documented.  In the past, I've taken as much as 250mg daily.

I agree with Pat that it seems you are on the starting dose of 50mg, but we don't know what other meds you are on or how long you've been taking Zoloft.  It takes anti-depressants a number of weeks to reach their full effect and we sometimes have to experiment with dosage to find right level.

Definitely talk to your doctor about your concerns, but here's what I found online:

Depression or Obsessive Compulsive Disorder

The usual starting dose is 50 milligrams once a day, taken either in the morning or in the evening. The doctor may increase your dose depending upon your response. The maximum dose is 200 milligrams in a day.

Premenstrual Dysphoric Disorder

Doses may be prescribed throughout the menstrual cycle or limited to the 2 weeks preceding menstruation. The starting dose is 50 milligrams a day. If this proves insufficient, the doctor will increase the dose in 50-milligram steps at the start of each new menstrual cycle up to a maximum of 100 milligrams per day in the 2-week regimen or 150 milligrams per day in the full-cycle regimen. (During the first 3 days of the 2-week regimen, doses are always limited to 50 milligrams.)

Panic Disorder, Post-traumatic Stress Disorder, and Social Anxiety Disorder

During the first week, the usual dose is 25 milligrams once a day. After that, the dose increases to 50 milligrams once a day. Depending on your response, you're the doctor may continue to increase your dose up to a maximum of 200 milligrams a day.