Hi Ricky: Actually, there is information about Wellbutrin causing skin problems as a side effect. Allergic-type reactions are not unheard of. Rashes, (hives), angioedema, dyspnea, (Stevens-Johnson Syndrome), and anaphylactic shock has been associated with bupropion. There are a wide array of side effects that a person can experience from antidepressants. You didn't indicate how long you have been taking this medication. If you have been taking this for a short while, this can be the reason that you are having these changes.  Side effects are the most noticeable in the very beginning.   I would strongly suggest you speak with your psychiatrist about this. It may pass, or may be due to something unrelated to the Wellbutrin, or you may need to change your medication.   Best of luck, Dr. Diana Walcutt   *Dr. Walcutt is a Psychologist. Dr. Walcutt's answers are not intended to diagnose or treat any medical or mental disorder. Any information given in a post about medication is for educational purposes only, and primarily to aid you in having an informed discussion with your own Psychiatrist/Physician.