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Hi, there.  Part of your question was cut off, but I think you're asking about Wellbutrin making you resistant to the effects of alcohol.  I've taken it for years and I haven't found that to be true.  I think different things affect tolerance for alcohol, including whether or not you've eaten recently, and I've discovered some wines have very little effect on me, but others definitely do.  Actually, I'm not sure you're supposed to drink while taking it, but I've not found it to be a problem.   Hope that help some - thanks for visiting our site!
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