Generic Name: BUPROPION EXTENDED-RELEASE (ANTIDEPRESSANT) -
ORAL Pronounced: (bue-PROE-pee-on) Wellbutrin XL Oral Precautions
See also How to Use and Warning Sections
Before taking bupropion, tell your doctor or pharmacist if
you are allergic to it or if you have any other allergies. This product may
contain inactive ingredients, which can cause allergic reactions or other
problems. Talk to your pharmacist for more details.
This medication should not be used if you have certain
medical conditions. Before using this medicine, consult your doctor or
pharmacist if you have:
eating disorders (e.g., bulimia, anorexia nervosa)
This medication should not be used if you are suddenly
stopping regular use of sedatives (e.g., benzodiazepines such as lorazepam) or
alcohol, which can cause a higher risk of seizures.
Before using this medication, tell your doctor or
pharmacist your medical history, especially of:
How long does withdrawal from Zoloft take, and are there any serious side effects that will damage the brain? As far as we know, SSRI withdrawal does not cause permanent damage. But it feels like a bad flu, so it's not fun. The withdrawal is based on two factors: the half-life of the drug and the "potency" of the drug. The short half-life drugs such as Paxil tend to produce worse withdrawal than longer half-life drugs, such as Prozac. Many psychiatrists take advantage of the long half-life of Prozac and prescribe a single dose to treat withdrawal from the other SSRIs. Importantly, there is cross-coverage from other drugs. Stopping Paxil cold will produce withdrawal, but switching Paxil to Zoloft, for example, should protect you from it. In addition, this withdrawal effect is (mostly) limited to serotonergic antidepressants. Wellbutrin is not expected to have this effect.
I've been taking Wellbutrin (generic name Bupropion) for about seven years, minus the time I was pregnant with my son. I would say that overall it's been very successful, except during one period. All of a sudden, even though I was faithfully taking my medicine, it was as though I was taking sugar pills. I realized that the color and size of the pills in my most recent prescription refill were different from the ones that I had been taking. It turned out that the pharmacy had started stocking a different brand of Bupropion. When I explained what was happening they ordered a bottle from the company they had previously been stocking. Within a few days I was back to normal. From then on I made sure that they filled my prescriptions using that specific company until I ultimately went back to taking the brand name version. I was not particularly surprised that the effectiveness of the generic version varied so widely between manufacturers. I know of someone who had a recurre...
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