Monday, February 13, 2012
Introducing Mood 24/7, a new tool that helps you track your mood from day to day using your mobile phone.Try it today!

Wednesday, September 10, 2008 Wendy asks

Q: Is it possible to become immune or so used to an antidepressant that it no longer helps??

I've been on Effexor XR for 10 years and for the last month I've had major highs and lows. The first 2 weeks were endless expenditures on stuff I couldn't afford and didn't need.Insomnia was a major problem. These last 2 weeks have been no energy, missing work, don't need to spend any money, quit exercise. Very low. I'm on 150 mg. Dr.appt. is Monday. Maybe I should up my dose or switch to Cymbalta. 

Answer This
Answers (3)
9/11/08 6:34pm

hi, i've been on almost every antidepressent and yes sometimes they just stop working, i'm on pristiq now which is the newest one on the market hopefully it doesn't stop working like all the others. i have been depressed for 18 years so that's along time. definitly try an increase or a new antidepressent. good luck. brendavo

Reply
9/11/08 2:49pm

Yes, now I'm no doctor. But, I know it happened to me. I was on an antidepressant for years and it stopped "working" for me. I talked to my neuro. and I was changed to another one. After taking some meds. for a long time, they can stop working for you.

 

Peace, dawn

 

 

 

Reply
9/15/08 5:26pm

 

 

Yes, i was on paxil 10mg for six years and it stopped working. My sister in law was also on it for the same length of time and it stopped working for her as well. She stopped the paxil and switched to lexapro ....no side effects. My doctor has me switching also but he wants me to stay on the paxil and gradually taper off until the lexapro is in my system. That's what im doing but not too happy to be taking both of them at once.  I just hope lexapro is an easier drug to get off.

Reply
Answer This

Important:
We hope you find this general health information helpful. Please note however, that this Q&A is meant to support not replace the professional medical advice you receive from your doctor. No information in the Answers above is intended to diagnose or treat any condition. The views expressed in the Answers above belong to the individuals who posted them and do not necessarily reflect the views of The HealthCentral Network. The HealthCentral Network does not review or edit content posted by our community members, but reserves the right to remove any material it deems inappropriate.

Ask a Question

Get answers from our experts and community members.

Btn_ask_question_med
View all questions (4088) >