Sudden improvement! Things have turned around!
I'm a 38 yr old female, married, one son. History of cyclical depression/OCD/GAD. Family history of mental illness requireing hospitalization, suicides, addiction. Latest years of dark, deep depression and anxiety (along with dependence on and withdrawal from prescribed meds) accompanied spinal surgeries following birth of my son in 2006.
Progressively took Paxil, then Prozac, Lyrica for GAD. Most recently Lexapro/Wellbutrin combo with brief, good initial results that tanked out after a couple of months. My PCP started me on Pristiq roughly three weeks ago.
Substituted Pristiq for Lexapro while continuing Wellbutrin -- no titrating Lex. Perhaps a bad idea but read on ...
First, experienced horrible period of depression and suicidal thoughts. Constant sweating, anxiety, restlessness, unable to concentrate, irritable to the point of screaming at my son and husband, who thought I should go inpatient at local psych ward. THEN -- on Thursday night I noticed I was able to concentrate on a movie all the way to the end and ENJOYED IT! Friday restless, irritable, hopeless, sweating, suicidal -- had a meltdown at a 4th of July parade party -- Saturday the same ... until Saturday night.
On Saturday night, I began to feel sort of "out of myself" beyond the realm of what had become normal for me. A lightness, an awareness that life was something I could enjoy and observe AND engage in ... Sunday went out with family all day, no meltdowns, panic attacks or overwhelming dread. Sunday night watched a movie with the family all the way to the end and ENJOYED IT! Talked with my husband all night, engaged in the conversation in a way I had forgotten I could.
This morning I leapt out of bed following full night's rest, went to work, walked into the building with a huge smile on my face -- I hope this is the reality Pristiq makes possible, and that it lasts.
FINALLY!!! I feel like I'm back after so many years in the dark.