Sunday, June 03, 2012
Introducing Mood 24/7, a new tool that helps you track your mood from day to day using your mobile phone.Try it today!

Saturday, March 21, 2009 Jeanne asks

Q: can effexor lose effectiveness after time?

I have been on 75s for several years; originally for SAD, but found it worked well with my depression (genetic through several generations).  My black moods where I had suicidal thoughts went away.  This week, though, I had a major one with 2 days straight of crying after a row with my spouse.  I literally made myself sick with the sadness.  Spouse is no help either as he is now doing the cold shoulder treatment even though he knows I have depression (yep, he has a mean side that doesn't help).  Before I would have been mad, but not suicidally depressed.  Have a call into my doc, but no return call yet (a problem with that office).  I have been thinking I need to change meds due to side effects, noticably huge weight gain and lack of energy.  If it fades after long term use, more reason.  I need a better quality of life than I have now.

Answer This
Answers (3)
Merely Me, Health Guide
3/22/09 10:01pm

Hi Jeanne

 

I am so sorry you are going through this.  Sometimes antidepressants can lose their effectiveness but sometimes difficult situations can make things just harder to cope. 

 

Here is some information about Effexor.

 

I am concerned that you are having suicidal thoughts.  I am going to give you some suicide hotline numbers just in case you just need someone to talk to.

 

1-800-273-TALK (8255)

  1800-784-2433

  1800-799-4889

 

Please let us know how you are doing.  I hope you are able to get in touch with your doctor soon.

 

 

Reply
3/22/09 9:00am
I am seeing my doctor monday. My complaint is also my effexor seems to not be working as well. I have been taken 150mg for five years. The biggest issue with my depression has always been fatigue. But during the last month or so it has become much worst. I could sleep all day if i let myself. I am going to see if i need to change meds. Will let you know how things work out. Good luck to you hang in there. Thanks Mike Reply
3/22/09 10:29pm

I have been on Effexor (75Mg.) 3 times per day for many years.  The past few years I have noticed I am depressed most of the time.  I was in a very verbally abusive relationship a few years ago, which also led me to thoughts of suicide at times.

My husband also gave me the cold shoulder or told me I was crazy.  I have wanted

to maybe try other medications, but my doctor just recently put me on Deplin.  It

is kind of like a vitamin supplement that is supposed to enhance the effects of

Effexor.  I've only been taking it a few weeks, but I haven't noticed much difference.

You might talk to your doctor about it.  It might help you.  I know it would also help

if you had more support from your husband.  I only wish more people knew how difficult it is to deal with deppresion and other mental or emotional disorders.

 

I hope I might have helped you in some way.

 

Sincerely,

 

Janet

 

Reply
Answer This

Important:
We hope you find this general health information helpful. Please note however, that this Q&A is meant to support not replace the professional medical advice you receive from your doctor. No information in the Answers above is intended to diagnose or treat any condition. The views expressed in the Answers above belong to the individuals who posted them and do not necessarily reflect the views of Remedy Health Media. Remedy Health Media does not review or edit content posted by our community members, but reserves the right to remove any material it deems inappropriate.

Ask a Question

Get answers from our experts and community members.

Btn_ask_question_med
View all questions (4165) >
By Jeanne— Last Modified: 12/26/10, First Published: 03/21/09