The FDA has approved EMSAM (selegiline), a transdermal patch,
for the treatment of major depression. Selegeline is a MAOI
originally used to treat Parkinsons. MAOIs belong to an old
class of antidepressants, typically used as a last resort. When
taken orally, side effects with these meds tend to be onerous,
including risk of tyramine reaction and resulting hypertensive
crisis, which necessitates severely restricting ones
The patch was developed by Somerset Pharmaceuticals, who
partnered with Bristol-Myers Squibb. Because the drug is absorbed
through the skin, there is little or no contact with gastric
tyramine and interactions with various enzymes. Based on three
small studies, the product labeling advises that a modified diet is
not required for 6 mg a day of EMSAM. But due to limited data, the
labeling advises that those on doses of 9 and 12 mg are required to
restrict their diets. If hypertensive crisis occurs, the drug
should be discontinued immediately and thera...
The American Council on Exercise’s most recent newsletter offered a list of super foods that are readily available during winter. One of these honorees is winter squash. I have to admit that I haven’t tried winter squash very often, but plan on doing so during 2013. So what’s so appealing about winter squash?
Lots of Nutritional Value According to Self’s Nutrition Facts , butternut winter squash has proven to be a great source of vitamin A (457 percent of the daily value per one cup serving), potassium (17 percent of the daily value), vitamin C (52 percent of the daily value) as well as a good source of niacin (10 percent of the daily value), folate (10 percent of the daily value), calcium (8 percent of the daily value) and iron (7 percent of the daily value). This vegetable is low-calorie (82 calories per one cup), fat free and cholesterol free. Other varieties of winter squash have equally impressive numbers.
The George Matlejan Foundation , which is a not...
One of the first studies to look at serious physical trauma in patients reveals that nearly a third of the patients studied sustained sexual dysfunction even after a year passed since the trauma event. This particular study involved over 10,000 patients and 69 hospitals across 14 states. The incentive to do the study was prompted by surgeons of young trauma patients who were receiving these complaints of sexual dysfunction even though a year's time had passed and adequate healing (regardless of the type of physical trauma) had occurred.
The rate of sexual dysfunction nearly doubled when comparing under age 50 trauma patients to healthy patients in the same age group; it nearly tripled in the over age 50 age group when compared to the over 50 healthy populace. What was also really provocative was that the statistics of sexual dysfunction did not depend on what kind of physical trauma had occurred. It was expected that if the serious trauma involved the pe...
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