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Hi-- I am now doing very well on the pristiq; Dr has added the wellbutrin;150mg as a booster. It took me about 8-10 weeks for it to really work well.  I like it for the low level of side-effects; the stomach problems are now gone; and I do not have the morning depression since last week. That was the last thing to work on. I think the wellbutrin helped with that too. I wish you well and just want to say to you not to give up on this because it takes longer than others I have been on but it does work well. Good luck to you and keep in touch!  Sandy                                                      
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