According to a new study of Savella (milnacipran) for the treatment of fibromyalgia, patients who continue treatment can get long-term pain relief – to at least three years. These findings were reported by Lesley Arnold, MD, professor of psychiatry at the University of Cincinnati College of Medicine in a poster presentation at the recent annual meeting of the American College of Rheumatology. Savella , the third drug to be approved for treating fibromyalgia, received its FDA approval in January 2009. This is the first study showing its long-term efficacy. Study Design and Results This was a four-phase clinical trial that originally included 1,268 patients. Similar relief was achieved by the 820 who took Savella for one year, the 462 who completed two years and the 217 who continued for three years. In the original group, 1,212 patients achieved a mean decrease of 17.6 points in their Visual Analogue Pain Weekly Recall, or Visual Analogue Scale (...
The goals of treatment are to reduce the immediate withdrawal symptoms, prevent complications, and begin long-term therapy to promote abstinence (no drinking at all).
People with moderate-to-severe symptoms of alcohol withdrawal may need inpatient treatment at a hospital or other facility that treats alcohol withdrawal. Others who may need inpatient treatment include those who:
Have a mental health disorder, such as schizophrenia or bipolar disorder
Have failed outpatient treatment for alcoholism or alcohol withdrawal
Have serious medical problems
May be harmful to themselves or others
Treatment at an inpatient center will include medical monitoring and treatment of alcohol symptoms.
Monitoring of blood pressure, body temperature, heart rate, and blood levels of different chemicals in the body will take place. The person will be watched closely for hallucinations and other signs of delirium tremens .
Alternative Names Withdrawal from nicotine; Smoking - nicotine addiction and withdrawal; Smokeless tobacco - nicotine addiction; Cigar smoking; Pipe smoking; Smokeless snuff; Tobacco use; Chewing tobacco Symptoms Nicotine use can have many different effects on body functions, both positive and negative. Nicotine acts as both a stimulant and depressant on your body. The use of nicotine: Decreases the appetite (for this reason, the fear of weight gain affects some people's willingness to stop smoking). Boosts mood and may even relieve minor depression. Many people will feel a sense of well-being. Raises the blood level of blood sugar (glucose) and increases insulin production. Increases bowel activity, saliva, and phlegm. Increases heart rate by around 10 to 20 beats per minute. Increases blood pressure by 5 to 10 mmHg (because it tightens the blood vessels). May cause sweating, nausea, and diarrhea. Stimulates memory and alertness. People who use tobacco often depend on it to help them accomplish...
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