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Sunday, February 15, 2009 Ann Thompson, Community Member, asks

Q: If I plan to take folate instead of 7.5 mg deplin, what amount of folate should I use?

My Dr. prescribed deplin and my insurance will not pay for deplin and I want to sub folate. How many mg should I take daily? AT
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Answers (1)
Merely Me, Health Guide
2/16/09 5:39pm

Hi Ann


I have information here about both Deplin  as well as a government fact sheet about folate.


In the research that I have done just now it seems that if you take too much folate, this can be medically harmful.  Check out what this web site has to say as a warning.


I strongly suggest that you ask your doctor how much folate you need to be using and if it is a good substitute.  I wouldn't want you to suffer needless adverse effects from taking too much.

kchild, Community Member
11/23/09 10:42am

Is Deplin Folic Acid or a medicine that helps your body access folic acid? I have read folic acid can mask deficiencies in B12."Folic acid: Folic acid, particularly in large doses, can mask vitamin B12 deficiency by completely correcting hematological abnormalities. In vitamin B12 deficiency, folic acid can produce complete resolution of the characteristic megaloblastic anemia, while allowing potentially irreversible neurological damage (from continued inactivity of methylmalonyl mutase) to progress. Thus, vitamin B12 status should be determined before folic acid is given as monotherapy" (WebMD)

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By Ann Thompson, Community Member— Last Modified: 12/18/10, First Published: 02/15/09