If the meds aren't working, and you're taking them as directed, and using them long enough to make sure that it's the med that isn't working, and not your emotional state screwing you up - then get another psychiatrist, and/or another talk therapist - you have to have both. I told doctors for 15 years that I was tired all the time - and it wasn't until I got a new psychiatrist who started me on Wellbutrin that I got my energy back - 15 years of fatigue, no motivation - I could function at work, but I was useless after I got home. So keep trying - keep asking, keep searching - you will find a solution, and it's about 80% up to you - the doctors and shrinks are only a few steps ahead, and sometimes they know less than we do!   I have a great talk therapist right now, who tells me what she sees in me - and is honest. Howrefreshing! I've felt the feelings, I know my baggage, now I'm trying to get to my behavior - my behind-the-scenes stuff. I have to get my self-esteem out of my emotional gutter, and she's helping me do that.   Don't be a martyr - make yoursef go look one more time for your solution - demand the truth, demand quality treatment, and live glass half full. Your family will suffer much more if you die than if you try.