I was asked to comment on Modafinil (Provigil®). It was originally approved by the Food and Drug Administration (FDA) in 1998 for the treatment of excessive daytime sleepiness associated with narcolepsy, and since then has gained FDA-approval for the treatment of excessive sleepiness associated with Obstructive Sleep Apnea, Hypoventilation Syndrome, and Shift Worker Sleep Disorder.
Notice what is missing: MS Related Fatigue. Although there have been studies demonstrating that it is safe and...

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