Several new medications for the treatment of depression have been introduced over the last 20 years. What has been missing is any consistent data about the effectiveness of these "second-generation" antidepressants.
A team of researchers have now reviewed 117 controlled trials to compare second-generation antidepressants for the acute treatment of unipolar major depressive disorder in adults. The medications were reviewed for efficacy (effectiveness), patient acceptability, and cost.
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