I wrote about CYP2D6, which refers to a gene that codes for a biologic molecule involved in the breakdown of tamoxifen, about a year ago. Since then it has not become standard of care to order this on patients taking tamoxifen, but my desire to do so has increased. Routine testing is not yet recommended, according to those in the know.
We refer to women who have two normal copies of this gene as having the "wild-type," which means normal type for the breakdown of...
Tamoxifen (Nolvadex) Effectiveness: Something to worry about?Over my morning coffee and one of the three daily newspapers I read I see a... Read more »
If you’re one of the tens of thousands of women taking tamoxifen to prevent new breast cancer or a recurrence, listen up: it may not be... Read more »
Discussed in this blog two years ago, many academicians now recommend testing for CYP2D6 metabolic signature to determine if postmenopausal... Read more »
Research on the possibility of a drug interaction between tamoxifen (nolvadex) and serotonin reuptake inhibitors (SSRIs) - a class of... Read more »
Thanks to fellow SharePoster Jolene Boyd, a startling issue involving tamoxifen was recently brought to light. Jolene’s recent post on... Read more »
Reporter Joanna Silberner looks at the case of a boy with autism who suffered adverse reactions to a medication because his body was not able to... Read more »
An experimental genetic test may be able to determine a patient's risk of breast cancer recurrence. U.S. researchers say the presence of two genes in... Read more »
A breast cancer patient asks Dr. Mitchell Hecht if her antidepressant will interfere with the drug tamoxifen. According to Dr. H, SSRI drugs like... Read more »
Statistics show that many breast cancer survivors take antidepressants to help control the hot flashes brought on by the use of the drug tamoxifen, a... Read more »
Source: Breastcancer.org
You've just finished chemotherapy and are ready to get pregnant. Then your doctor says you should start tamoxifen. Tamoxifen is a hormonal therapy... Read more »
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