Side Effects Of Saint Johns Wort

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St. John's Wort Reduces Oxycodone Effectiveness

It's not unusual for people living with chronic pain to also be dealing with some depression and/or anxiety.  But if you're taking an opioid like oxycodone for the pain and also taking an herbal supplement containing St. John's Wort, you may unknowingly be reducing the effectiveness of your pain medication.  

A small study in Finland found that when St. John's Wort and oxycodone were taken together, the plasma concentration of oxycodone decreased by 50 percent and its half-life (the time it...

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