Depression Education Center
This special section and content brought to you by Forest Pharmaceuticals Inc.
The Health Channel Network
Understanding Depression

How Common is Depression?

Approximately 15 million American adults suffer from major depressive disorder (MDD) every year.1 In fact, 1 out of every 6 people will suffer from major depression at some point in their life.2 Experts predict that by the year 2020, major depression will be the second most important cause of disability throughout the world.2

The Chemistry of Depression

The brain chemistry of depression and anxiety is not fully understood. However, a growing body of evidence supports the view that people with these disorders have an imbalance of the brain's neurotransmitters - chemicals in the brain that allow nerve cells to communicate. One of these neurotransmitters is serotonin. An imbalance in serotonin may be an important factor in the development of depression and anxiety. Regardless of the cause, most depression is highly treatable.

References: 1. Kessler RC, Chiu WT, Demler O, Walters EE. Prevalence, severity, and comorbidity of twelve-month DSM-IV disorders in the National Comorbidity Survey Replication (NCS-R). Archives of General Psychiatry, 2005 Jun;62(6):617-27. 2. Davidson JR, Meltzer-Brody SE. The underrecognition and undertreatment of depression: what is the breadth and depth of the problem? J Clin Psychiatry. 1999;60(Suppl 7):4-9.