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Pristiq Oral Precautions and Side Effects


IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate or effective for you. Consult your healthcare professional before using this drug.

Table of Contents

Generic Name: DESVENLAFAXINE SUSTAINED RELEASE - ORAL
Pronounced: (des-VEN-la-FAX-een)

Pristiq Oral Precautions

Before taking desvenlafaxine, tell your doctor or pharmacist if you are allergic to it; or to venlafaxine; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of:

  • personal or family history of psychiatric disorders (e.g., bipolar/manic-depressive disorder)
  • personal or family history of suicide attempts
  • bleeding problems
  • glaucoma
  • high blood pressure
  • heart problems (such as chest pain, heart failure, heart attack)
  • history of stroke
  • high cholesterol
  • kidney disease
  • liver disease
  • seizure disorder
  • low sodium in the blood (hyponatremia)

This drug may make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Avoid alcoholic beverages.

Kidney function declines as you grow older. This medication is removed by the kidneys. Therefore, older adults may be at greater risk for side effects (e.g., bleeding) while using this drug. The elderly are more likely to lose too much salt (hyponatremia), especially if they are also taking "water pills" (diuretics) with this medication.

Based on information for a similar drug (venlafaxine), this drug may affect growth rate in children. Therefore, caution is advised if this drug is used in children. Monitor your child's height and growth rate. Consult your doctor or pharmacist for more details.

Use this medication only when clearly needed during pregnancy. It may harm an unborn baby. Also, babies born to mothers who have used this drug during the last 3 months of pregnancy may infrequently develop withdrawal symptoms such as feeding/breathing difficulties, seizures, muscle stiffness, or constant crying. If you notice any of these symptoms in your newborn, tell the doctor promptly.

Since untreated depression can be a serious condition, do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss the benefits and risks of using this medication during pregnancy with your doctor.

This drug passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.

Pristiq Oral Side Effects

See also Warning section.

Drowsiness, dizziness, nausea, dry mouth, constipation, loss of appetite, weight loss, blurred vision, nervousness, trouble sleeping, or excessive sweating may occur. If any of these effects persist or worsen, tell your doctor promptly.

Desvenlafaxine may increase blood pressure. Your blood pressure should be checked regularly while you are taking this medication.



CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
Information last revised September 2011 Copyright(c) 2011 First DataBank, Inc.