I also use a combination of Humalog and Lantus, and one would perhaps think that Humalog, the fast-acting insulin, would be more dangerous of the two but not true in my case. I've probably had 4 or 5 episodes where I've been to the point of almost being incapacitated because my sugar dropped so quickly after taking Lantus. And not only just quick drops, but profound, stubborn lows that were not easy to get back up. During one or two of the incidents I doubt whether I would have been able to recover had I not had someone with me. Scary stuff indeed. I use very short, fine needles and always inject in the most "padded" part of my belly, so not sure about any accidental intravenous injections? I inject Humalog in exactly the same places and haven't had any trouble with a great many more injections.
I'm 40+ years type 1. Started on Lantus 3 years ago, and have hade several of these "hot shot" episodes. It seems that there are times, though rare, when this insulin type rares it's ugly head and bites with a vengence. I will try splitting the dose and taking it during waking hours as I was taking it at bedtime (16 u.) and once or twice a year crashing severely in about 1-2 hours. This is w/ a bs of over 130 before bed, and a full 8 hours after my dinner Novolog dose. I started thinking "why"? This IS definately every bit as dangerous as fast acting doses, and maybe even more so, because you generally aren't expecting it. The low's are profound ( <30) and longer lasting. Immediate attention is called for. Take care!!!
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I experienced exactly the same problem. The split of Lantus doseage (10+10 in my case) solved the issue. With fast action insulin an Hypo condition is fast to occur but it goes away fast if the right ammount of CH is taken. With Lantus Hypo episodes they are recurrent (they keep coming back, it is a bit scarrying tough) even after taking the ammount of CH thought required for the first episode. But all in all,
Lantus+Fast Insulin is yet to be beatten for great BG control
FFaria, Portugal