"But for those of us with type 2 diabetes, it could be even better news to use metformin or Byetta. Neither of these medications lead to hypos. And metformin is weight neutral, while Byetta can lead to substantial weight loss."
David, please remember that just because Byetta and metformin work for you does not mean that it works for all type 2's. I am one of them, byetta worked for only 2 1/2 hours after shot and then my bG would start elevating rapidly with no weight loss and when I was given metformin(the first prescribed drug) my bG continued to rise and it seemed like metformin did nothing. I still take metformin but it still does not seem to do anything. I currently take Januvia and it seemed to help some but it was only when I was prescribed Lantus that my bG started to go down. FYI I have never had a hypo and I have taken Lantus for 6 months. My A1c is down from 7.8 to 6.6.
cindy
If diabetics were taught how to use insulin properly there would be a lot less hypos.
First of all, mixed insulins are OUT. One shot is nice but it rarely works to maximal benefit.
Diabetics on insulin need to take a basal (long acting) insulin for background (between meal) coverage and then a fast-acting insulin such as Novolog or Humalog MATCHED TO CARBS EATEN AT THE UPCOMING MEAL like pumpers do, for best effect. For this, they need to know their carb to insulin ratio. There are mighty few doctors who understand this and even fewer insulin using diabetics who do. It takes some work and experimentation. But the end result is excellent glucose control with minimal hypos.
My husband is a type II diabetic and must take insulin because of other health problems that affected his kidneys. Oral diabetic medication is too hard on his kidneys. I think it is almost criminal how much pharmaceutical companies and pharmacies charge for insulin. The costs in Canada are so much lower for the same product. People should write to their congressmen and congresswoman as well as Senators urging passage of the bill to allow for development and marketing of generic insulin. It's time citizens were heard regarding the high cost of health care in this country. Special interest groups have too long influenced our elected officials to our detriment.
David,
While the lack of generic versions is an obvious answer to the high and rising pricing of insulin, it seems to me that the problem is much more complex.
Consider the pricing of test strips. Three hundred Lifestyle strips shows a retail price of $325, up from $240 not too many years ago. It would be hard to argue that the test strip market is not highly competitive, and there is not even a requirement for a prescription for purchase. While test strips are not interchangeable between meters, the monetary cost to change meters is minimal, even if they were not available for free. (learning curve costs might be more significant).
It is more likely that the high retail prices are the result of the fact that the insurance companies dominate the demand and the dollar sales yield comes almost completely from the discounted and rebated insurance company payments. Raising the retail price doesn't reduce company revenue to any great extent and may even increase it to the extent that the retail prices may set a reference point for discounts.
It seems likely that, in many cases, retail drug prices are above the prices that a monopoly producer would maximize his profit by charging on a free market if it weren't for the third party payment environment of the insurance companies.
Regards, Don
I don't doubt that the insulin market in the U.S. is approaching monopolistic pricing. But that's not true with test strips. Yes, the LifeScan test strips are expensive. According to a review this month in Diabetes Health magazine their list price is $0.94 each. But other test strips list for as little as $0.35 each.