Who Benefits Most from Bydureon

David Mendosa Health Guide June 27, 2012
  • A new medication that those of us who have type 2 diabetes take only once a week can bring our A1C levels way down. It can also help us to lose weight, something that almost everyone who has type 2 diabetes needs to do.But predicting who will lose weight isn’t easy. Only one thing stood out in ...

9 Comments
  • Anonymous
    Tom
    Dec. 13, 2013

    Dear Kahn,

    I've had diabetes for about ten years. I'm 65 years old.

    For years my GP has had me on Actoplus Met and Januvia.

    In Sept 2013 my weight was 288 and my A1c was 9.3

    My typical fasting blood sugar level was 170.

    My GP urged me strongly to see an Endocrinologist.

    The Endocrinologist put me on Lantus 15mg per night.

    I also went on a low carb diet with...

    RHMLucky777

    Read More

    Dear Kahn,

    I've had diabetes for about ten years. I'm 65 years old.

    For years my GP has had me on Actoplus Met and Januvia.

    In Sept 2013 my weight was 288 and my A1c was 9.3

    My typical fasting blood sugar level was 170.

    My GP urged me strongly to see an Endocrinologist.

    The Endocrinologist put me on Lantus 15mg per night.

    I also went on a low carb diet with no caloric restrictions.

    Two weeks later my fasting BGL was typically 90. Weight was 284.

    He cut me back to Lantus 8mg per night.

    Six weeks later my fasting BGL was typically 105. Weight was 279.

    He took me off Lantus and replaced it with Bydureon 2mg, once weekly.

    Four weeks later my fasting BGL was 89 and my A1c was 5.9, weight 275.

    He took me off Januvia and so far things seem about the same.

    Bydureon seems to be almost like magic, at least for me.

    My Endocrinologist chose not to mix Bydureon and Lantus.

    In my short three months with these two drugs it appears that Bydureon is not only equally effective, it is much more even keeled with regard to BG levels.

    I know that no two people react the same to any given medication.

    For me at least, Bydureon has been remarkably effective.

     

  • Andy1234
    Jun. 29, 2012

    Is there any information on combining long acting insulin and Bydureon?  The long acting insulin I take is causing weight gain and a combination might be helpful.  Any thoughts would be appreciated.  Thanks

    • David Mendosa
      Health Guide
      Jun. 29, 2012

      Yes, insulin generally does lead to weight gain. And while Bydureon might offset that a little, the combination generally also leads to weight gain. Still, insulin doesn't have to lead to weight gain, but that means you have to take just the right kind at the right time in the right amount.

    • Andy1234
      Jul. 01, 2012

      Thank you for the reply......still working on the food issue!

    • Dr. Bill Quick
      Health Pro
      Jul. 03, 2012

      There's lots of information in the Bydureon USPI about using Bydureon with insulin glargine (Lantus):

      http://documents.bydureon.com/Bydureon_PI.pdf

      Bydureon is being studied with Levemir (insulin detemir), but the USPI doesn't mention it, as the trial is presently "ongoing"

      http://clinicaltrials.gov/ct2/show/NCT01003184

       

      Hope this helps!

      Bill

      William...

      RHMLucky777

      Read More

      There's lots of information in the Bydureon USPI about using Bydureon with insulin glargine (Lantus):

      http://documents.bydureon.com/Bydureon_PI.pdf

      Bydureon is being studied with Levemir (insulin detemir), but the USPI doesn't mention it, as the trial is presently "ongoing"

      http://clinicaltrials.gov/ct2/show/NCT01003184

       

      Hope this helps!

      Bill

      William W. Quick, MD, FACP, FACE

      Editor, D-is-for-Diabetes

      http://www.D-is-for-Diabetes.com/index.htm

       

    • Anonymous
      Khan
      Oct. 29, 2013

      Sir, I am taking Lantus morning and at night and Humalog 3 time with every meal. So If I take Bydureon what do I need to stop the Humalog or the Lantus. If Humalog why and if Lantus why. Please if you could take some time out for my question I will appricate it.

      Thanks.

       

      Khan. 

    • David Mendosa
      Health Guide
      Oct. 29, 2013

      Dear Khan,

       

      First, since you are taking two types of insulin, I have to ask if you have type 1 diabetes. Bydureon is not prescribed for type 1.

       

      But if in fact you have type 2, Bydureon makes a lot of sense. When you start it, you will have to watch your blood glucose levels VERY carefully, because especially when combined with insulin, they are...

      RHMLucky777

      Read More

      Dear Khan,

       

      First, since you are taking two types of insulin, I have to ask if you have type 1 diabetes. Bydureon is not prescribed for type 1.

       

      But if in fact you have type 2, Bydureon makes a lot of sense. When you start it, you will have to watch your blood glucose levels VERY carefully, because especially when combined with insulin, they are likely to go hypo. My guess is that very soon your levels will be so good that you will no longer need insulin, but you and your doctor will have to decide when to stop the insulin.

       

      Do no harm,

       

      David

    • Dr. Bill Quick
      Health Pro
      Oct. 29, 2013

      Khan:

      You asked whether to cut back on Humalog (short-acting insulin) or Lantus (long-acting insulin) if starting Bydureon. My guess would be that your physician will advise cutting back on the Lantus, as Bydureon is also a long-lasting medication. However,  the decision would be influenced by your blood glucose values and your overall control.

      Hope this...

      RHMLucky777

      Read More

      Khan:

      You asked whether to cut back on Humalog (short-acting insulin) or Lantus (long-acting insulin) if starting Bydureon. My guess would be that your physician will advise cutting back on the Lantus, as Bydureon is also a long-lasting medication. However,  the decision would be influenced by your blood glucose values and your overall control.

      Hope this helps.

      Bill

      William W. Quick, MD, FACP, FACE

      Editor, D-is-for-Diabetes.com

    • David Mendosa
      Health Guide
      Oct. 29, 2013

      Dear Bill,

       

      Thanks for adding your comment.

       

      By the way, please note my new signature. While it is essentially the same as the Hippocratic Oath you took, I mean it not only that way but more generally, in EVERYTHING we do.

       

      Do no harm,

       

      David