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Monday, November, 23, 2009
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Shedding Light on the Co-morbidities of DiabetesThe Complications of Having Rheumatoid Arthritis and Diabetes

The PLAC Test

David Mendosa
David Mendosa
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Medical Journalist Living with Diabetes and Author of Fitness and Photography for Fun, www.mendosa.com/fitnessblog

After earning a B.A. with honors from the University of California,...

David Mendosa

Sunday, October 18, 2009
View All of David Mendosa's Posts
We now have a test that can determine hidden risks of heart attack and stroke. It's called the PLAC Test and is the only blood test that the U.S. Food and Drug Administration has approved.   The PLAC test helps us identify hidden risks for heart attack and stroke by measuring for Lp-PLA2. Thi...
  1. Cost
    Anonymous
    Sunday, October 18, 2009 at 08:51 PM

    For others curious . . LpPLA2 test listed at personalabs.com is $190.

     

    http://www.personalabs.com/194-Test-Detail-LpPLA2-Lipoprotein-associated-Phospholipase-A2.aspx

    Reply
    re: Cost
    David Mendosa
    Sunday, October 18, 2009 at 09:05 PM

    That's too high. LabCorp charged me $105. And the cash price at most labs is less than $75, according to a message that Justin Peterson, the business development manager for diaDexus, sent me.

    Reply
  2. Untitled Comment
    Gretchen Becker
    Monday, October 19, 2009 at 09:55 AM

    I think one thing we have to ask ourselves before getting an expensive test is, "What will I do differently if my results are bad?"

     

    If you're currently living on pizza and beer and you find you have a high risk of heart attack, then getting a warning that you're at high risk might be the kick in the butt you need to change your lifestyle.

     

    But it's my understanding that Lp(a) is primarily genetic, and there's not too much we can do about it except try to make sure our other lab test results are good. If they're already good, like David's, and if we already get a lot of exercise, like David, then what more can we do?

     

    In the future, I'm sure they'll be able to draw up a personal prescription on the basis of genetic predispositions and responses to different drugs. But now we're mostly in the dark.

     

    For example, some people claim you should avoid saturated fat. Other people claim that saturated fat is healthy. I suspect the real answer depends on both your personal chemistry and how much fat you're eating.

     

    For example, if you're not eating much fat, perhaps a little more sat fat would be beneficial. But thinking "saturated fat is good for me" and slurping down huge piles of lamb fat with every meal might do just the opposite.

     

    I read one study that showed that the monounsaturated fat in olive oil is beneficial, but there was also a comment saying that the beneficial effect was lost if you ate too much of it. Most people won't notice that caveat. They'll think, "Olive oil is good for you" and they'll eat too much.

     

    So, David, if your calcium scores are bad, or, more likely, slightly above normal for your age, what will you do differently?

     

     

    Reply
    re: Untitled Comment
    David Mendosa
    Monday, October 19, 2009 at 02:25 PM

    Dear Gretchen,

     

    Interesting question. The only thing I easily could do is to cut back on supplemental calcium in my multi-vitamin and/or multi-mineral pills.

     

    Best regards,

     

    David

    Reply
    re: re: Untitled Comment
    frankenduf
    Thursday, October 22, 2009 at 04:03 PM

    also could be related to supplemental vitamin D

    Reply
    re: re: Untitled Comment
    Renee
    Friday, November 06, 2009 at 09:05 PM

    Hi David

    Long time no talk.  Fyi, since I have recently found that my calcium score is over 1000 (which is bad since the ideal is 0), I have queried my cardiolgist about reducing my calcium intake,  He says that the ingested calcium has nothing to do with the buildup of calcium in the blood vessels.  The only thing to do is to follow the protocol for the cardiovascular problems, increasing exercise and watching nutrition in hopes of keeping it from going higher.

    Renoozie

    Reply
    re: re: re: Untitled Comment
    David Mendosa
    Friday, November 06, 2009 at 09:18 PM

    Dear Renee,

     

    Calcium scores are something high on my list of problems to understand better. I hope that your message will trigger more knowledgeable replies than mine. Your doctor's advice to watch your nutrition and hope sounds completely unhelpful to me. I have a feeling that he or she doesn't know any more about calcium scores than you or I do. Do others?

     

    Best regards,

     

    David

    Reply
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