The Most Effective Treatment for Type 2?

Gretchen Becker Health Guide
  • A recent meta-analysis has suggested that combining long-acting insulin with a GLP-1 (glucagon-like peptide 1) agonist may be the “most effective” drug treatment for type 2 diabetes, meaning the best blood glucose (BG) control with the fewest side effects.   GLP-1 is a hormone secret...

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Published On: September 16, 2015
18 Comments
  • David
    Feb. 20, 2015
    I have friends, and family that have Diabetes. On Oct 10 2014 I went for a DOT Physical. The Doctor informed me that my blood sugar was 453, and by Nov 11,2014 I couldn't see and I had lost 38 pounds of weight. My eye Dr. had me do an A1 blood test, It came back 13.5 At that point I looked into what my options are ????? Well I didn't want to have my feet cut...
    RHMLucky777
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    I have friends, and family that have Diabetes. On Oct 10 2014 I went for a DOT Physical. The Doctor informed me that my blood sugar was 453, and by Nov 11,2014 I couldn't see and I had lost 38 pounds of weight. My eye Dr. had me do an A1 blood test, It came back 13.5 At that point I looked into what my options are ????? Well I didn't want to have my feet cut off, or my hands, I had seen some other people live and die with Diabetes. I did find help, from face book of all places,, DiabetesProtocol.com After reading what this had to offer, I have a A1 of 6.8 my blood sugar is between 75-125 most of the time....After the short time of two months. I try to fallow the diet as best as I can. I have my sight back now (THANK GOD) and I am not on any kind of insulin. My Dr. told me that my liver levels are right where they are suppose to be, as well are my kidneys. She told me that my good cholesterol was good as well,It is right were it needs to be. My bad cholesterol was high, But she hopes that that might be brought down by adding fish oil to my diet. Well I hope that other people who read this will look into the facts ,,,,,, Don't take my word for it, Just try it
    • Gretchen Becker
      Health Guide
      Feb. 20, 2015
      David, I'm glad you're doing so well. Readers should know that Diabetes Protocol is a commercial program you have to buy. It claims to cure diabetes, which is usually a red flag.
    • David
      Feb. 20, 2015
      It does work,, understand that !!! Some people don't want to pay for insulin to go into their bodies, and there are other ways of treating Diabetes. My Dr. does not like the fact that my blood levels are were they are, she and I in fact made a deal,, (That if my blood levels were higher than 125 in the mornings) That I would go on her insulin. She lost Now...
      RHMLucky777
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      It does work,, understand that !!! Some people don't want to pay for insulin to go into their bodies, and there are other ways of treating Diabetes. My Dr. does not like the fact that my blood levels are were they are, she and I in fact made a deal,, (That if my blood levels were higher than 125 in the mornings) That I would go on her insulin. She lost Now she wants me to start checking my blood sugar 2 hours after my meals. Once again she is losing I am just letting people that read this know that there is other was of treating Diabetes without more and more drugs. Thank You for letting me
  • Daryl
    Dec. 04, 2014
    I've been on Januvia (100mg) for over a year along with metformin. It seems to "flaten" the higher numbers in the day time to around 105-110, but night time numbers to up to around 140. I've asked my doctor about trying the GLP-1 like Victoza, and he is very resistant to changing. He says that Januvia is "good enough." Last A1C was 6.5. Yet with strenous daily...
    RHMLucky777
    Read More
    I've been on Januvia (100mg) for over a year along with metformin. It seems to "flaten" the higher numbers in the day time to around 105-110, but night time numbers to up to around 140. I've asked my doctor about trying the GLP-1 like Victoza, and he is very resistant to changing. He says that Januvia is "good enough." Last A1C was 6.5. Yet with strenous daily exercise, and low carb eating I cannot seem to better this number. Do you have an opinion regarding these two types of drugs? I would like to somehow do better, but the doctor seems to think I am "good enough."
    • Gretchen Becker
      Health Guide
      Dec. 04, 2014
      Daryl, I'm not a physician, and even a physician can't give medical advice over the Internet without knowing all the details about a patient's other medical history, etc. So I don't know what is best for you. However, if it were me, I'd prefer Byetta. The DPP-4 inhibitors do inhibit the enzyme that breaks down GLP-1, but they also inhibit enzymes that break...
      RHMLucky777
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      Daryl, I'm not a physician, and even a physician can't give medical advice over the Internet without knowing all the details about a patient's other medical history, etc. So I don't know what is best for you. However, if it were me, I'd prefer Byetta. The DPP-4 inhibitors do inhibit the enzyme that breaks down GLP-1, but they also inhibit enzymes that break down other compounds, and no one knows the long-term effects of this. You can search on "DPP-4 side effects" and "Byetta side-effects." If you're not happy with your doctor's approach, can you find a new doctor? You say you're on a LC diet. How do you define low carb?
    • Gretchen Becker
      Health Guide
      Dec. 04, 2014
      Daryl, Another possibility is that you're not really type 2 but some kind of type 1 like LADA. Have you looked into this? Or have you discussed taking a long-lasting basal insulin like Lantus or Levemir?
  • MacDSmith2
    Dec. 02, 2014
    Why were you not happy with an A1C level of 6? I would think anything under 7 would be very welcome for type 2 people. I recently got mine to 6.8 and I'm very happy with that!
    • Gretchen Becker
      Health Guide
      Dec. 02, 2014
      Because real normal A1cs are in the 4s, so as long as one isn't having hypos, the lower the better, in my opinion. When you're on a low-carb diet, you can have lower BG levels without the peaks and valleys you get with more carbs.
    • Martin
      Jan. 19, 2015
      I'm not as knowledgeable as Gretchen about these things, but I think that recent studies have shown that mortality rates for type 2 diabetics, when blood glucose is "well controlled" i.e. kept to around normal levels for non-diabetics, is actually higher than for those diabetics who have higher A1c levels of around 6. Why this is so is not known. I wonder if...
      RHMLucky777
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      I'm not as knowledgeable as Gretchen about these things, but I think that recent studies have shown that mortality rates for type 2 diabetics, when blood glucose is "well controlled" i.e. kept to around normal levels for non-diabetics, is actually higher than for those diabetics who have higher A1c levels of around 6. Why this is so is not known. I wonder if Gretchen has a view upon this.
    • Gretchen Becker
      Health Guide
      Jan. 19, 2015
      Martin, Are you referring to the Accord study? That showed that tight control increased mortality. But they later did more analysis and found that the patients who did poorly were those who *tried* to reach lower BG levels (so they were in the tight-control group) but didn't succeed. These were all patients with pre-existing heart disease (they hoped a lot...
      RHMLucky777
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      Martin, Are you referring to the Accord study? That showed that tight control increased mortality. But they later did more analysis and found that the patients who did poorly were those who *tried* to reach lower BG levels (so they were in the tight-control group) but didn't succeed. These were all patients with pre-existing heart disease (they hoped a lot would die so they'd get good statistics). So you had very sick patients being given a ton of drugs in an effort to get A1c lower. In many cases it didn't work, and in others there was a lot of hypoglycemia. See http://www.medscape.com/viewarticle/723254 You might have to register to view, but it's free. ". . . the current analysis suggests that failure to respond (rather than a good response) to intensive therapy might somehow be associated with higher risk for death. " http://www.ncbi.nlm.nih.gov/pubmed/20427682 Unfortunately many physicians are misinterpreting this study.
  • bonnynemia
    Oct. 09, 2014

    Based on my own 23+ years of experience with my type 2 diabetes, the most effective treatment for myself is daily exercise (stair-running, power walking, jogging in place, or modified push-ups).

     

    The foods I have been eating since after my diagnosis have been heart-healthy, natural, fresh (raw or cooked), unprocessed, and whole, and they are mostly carbohydrates....

    RHMLucky777

    Read More

    Based on my own 23+ years of experience with my type 2 diabetes, the most effective treatment for myself is daily exercise (stair-running, power walking, jogging in place, or modified push-ups).

     

    The foods I have been eating since after my diagnosis have been heart-healthy, natural, fresh (raw or cooked), unprocessed, and whole, and they are mostly carbohydrates. I very well know that carbohydrates are notorious for creating fasting and post-meal blood sugar highs but they have not adversely affected my health yet. Maybe because they are short-lived.

     

    Most of my past A1c's were between 5.2% and 6.3%, the latest one I got on October 1, 2014, was 6%.

     

    I don't have any diabetes complications and I have never had any hypo problems. I am healthier than I can ever imagine and consequently, I am now entertaining the idea that maybe type 2 diabetes is not a progressive disease. Yes, I will always be a diabetic but having the privilege to enjoy life like I have no diabetes makes me feel very confident of reaching my 100th birthday as healthy as I am now.

     

    Bonny Damocles

    Male, 79 years old

    Height: 5'7"

    Weight: 139 lbs.

    Diagnosed as a type 2 diabetic in July 1991

    Diagnosis based on fasting bs reading of 468 mg/dl

    Only anti-diabetes medication since diagnosis: Daily Exercise

    • Gretchen Becker
      Health Guide
      Oct. 11, 2014

      Bonny, I'm glad you've found a program that works for you. I agree that whole foods are the best. The amount of carbohydrate someone can eat depends on how many beta cells have been destroyed, and this can vary from person to person.

       

       

    • bonnynemia
      Oct. 11, 2014

      Gretchen,

       

      Thank you very much for your reply.

       

      Yes, the number of healthy beta cells truly come into play when a type 2 diabetic eats a lot of carbohydrates.

       

      The question I have always been asking myself since my diagnosis is: How badly has type 2 diabetes damaged me considering the fact that the basis of my diagnosis was a fasting blood...

      RHMLucky777

      Read More

      Gretchen,

       

      Thank you very much for your reply.

       

      Yes, the number of healthy beta cells truly come into play when a type 2 diabetic eats a lot of carbohydrates.

       

      The question I have always been asking myself since my diagnosis is: How badly has type 2 diabetes damaged me considering the fact that the basis of my diagnosis was a fasting blood sugar reading of 468 mg/dl. I was required to be on several anti-diabetes pills, but I refused to take them. I would surely be not as healthy as I am now had I taken those pills.

       

      My personal observation of other type 2s who were diagnosed based on similar blood sugar reading as I had and who agreed to be on pharma anti-diabetes drugs unfortunately have not been doing as well as I have.

       

      Regards,

       

      Bonny Damocles

    • Gretchen Becker
      Health Guide
      Oct. 11, 2014

      Bonny, You don't know that it's the pills that harmed your acquaintances, unless you mean that by taking the pills, they thought they didn't have to adjust their diets. A lot of people have that attitude, alas.

       

      The way to see whether or not your high BGs harmed your beta cells is to get an A1c test.

       

      There's so much about this disease we still...

      RHMLucky777

      Read More

      Bonny, You don't know that it's the pills that harmed your acquaintances, unless you mean that by taking the pills, they thought they didn't have to adjust their diets. A lot of people have that attitude, alas.

       

      The way to see whether or not your high BGs harmed your beta cells is to get an A1c test.

       

      There's so much about this disease we still don't understand. Carbs with little fat make BG go up quickly and come down more quickly. Low carb with more fat makes BG not go up so fast or so high, but it comes down more slowly.

       

      So which is worse in the long run? We don't know. In your case, it sounds as if the high-carb diet is working for you.

    • Gretchen Becker
      Health Guide
      Oct. 11, 2014

      Bonny, Oops. I typed "A1c" when I meant "C-peptide." The C-peptide test gives you an approximation of how much insulin  you are producing.

    • bonnynemia
      Oct. 11, 2014

      Gretchen,

       

      It is very encouraging to know from you that nobody knows what type 2 diabetes is. Thank you very much for saying so.

       

      I never had a C-peptide test. Our family doctor who diagnosed me as a type 2 diabetic was a cardiologist who knew more about heart disease than diabetes. When I refused to take the pills he prescribed, he required me...

      RHMLucky777

      Read More

      Gretchen,

       

      It is very encouraging to know from you that nobody knows what type 2 diabetes is. Thank you very much for saying so.

       

      I never had a C-peptide test. Our family doctor who diagnosed me as a type 2 diabetic was a cardiologist who knew more about heart disease than diabetes. When I refused to take the pills he prescribed, he required me to take a stress test to find out my heart's condition. After passing it, he jokingly said that exercising as hard and as long as I could would not kill me.

       

      After 10 days of daily stair running, my blood sugar readings were already in the 130 mg/dl range. So very early in my life as a diabetic, I knew for sure that daily exercise would be the best, safest, longest lasting, and cheapest anti-t2d med for me.

       

      Have I been wasting my time and effort to find out what causes other type 2s to suffer miserably from their disease? No, because I have been very busy studying what my body, mind, and spirit need to stay healthy, productive, and happy.

       

      So far, I have learned that I should avoid all negative emotions like hating, worrying, envying, arguing, fighting with others, blaming God. I have also learned that I don't have to treat my type 2 diabetes for as long as my mind and body do a good job in putting to good use all the food nutrients that I take in. 

       

      Type 2 diabetes will be with me all my life and that's good for me because it reminds me all the time to eat the right foods, to drink only water, to be mentally and physically busy during the day, to have enough rest at night, to feel the sunshine on sunny days, and to be good to all God's creations.  

       

      May I get your permission to share our conversations with all my friends who have type 2 diabetes whom I have met at ADA and UK diabetes forums.

    • Gretchen Becker
      Health Guide
      Oct. 12, 2014

      Bonny, Feel free to quote me on your lists. But please provide a link to this blogpost so my comments aren't taken out of context.

       

      I don't agree that "nobody knows what type 2 diabetes is." We know a lot about type 2 diabetes. It's just that, as always in science, there's also a lot we don't know yet. Plus some people are diagnosed with type 2 when they...

      RHMLucky777

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      Bonny, Feel free to quote me on your lists. But please provide a link to this blogpost so my comments aren't taken out of context.

       

      I don't agree that "nobody knows what type 2 diabetes is." We know a lot about type 2 diabetes. It's just that, as always in science, there's also a lot we don't know yet. Plus some people are diagnosed with type 2 when they have another type of diabetes like MODY or ketosis-prone diabetes. There may be other uncommon forms of diabetes that haven't been discovered yet.

       

      You have a good attitude about your own diabetes. Keep it up.

    • bonnynemia
      Oct. 12, 2014

      Gretchen,

       

      Thank you very much for saying that I have a good attitude about my diabetes.

       

      When I said that nobody really knows what type 2 diabetes is, it is my way of saying that it is a mysterious disease considering the fact that a type 2 diabetic like me has lived for more than 23 years and counting like I don't have it. Nearly everything that...

      RHMLucky777

      Read More

      Gretchen,

       

      Thank you very much for saying that I have a good attitude about my diabetes.

       

      When I said that nobody really knows what type 2 diabetes is, it is my way of saying that it is a mysterious disease considering the fact that a type 2 diabetic like me has lived for more than 23 years and counting like I don't have it. Nearly everything that experts on type 2 diabetes say should be done by type 2s have been ignored by me and amazingly I am still alive and healthy. 

       

      How often should type 2s test their blood sugar and what should they test for?

       

      I test only 100x/year to find out if my daily exercise is still doing its job. I don't need to find out if my fasting and post-meal blood sugar readings are high. I already know that they are always high because of my heavy carbohydrate intake.

       

      Type 2s have to test their blood sugar before exercising because if it is low, they have to eat something to raise it. I always do my exercise immediately before each meal and before going to bed and I don't worry about having low blood sugar reading. There is no reason for me to get it. I have never had it since my diagnosis. Hunger and physical and mental activities don't cause it, per my experience.

       

      Type 2 diabetes is a progressive disease according to all the experts I have known. In my case, I am the one progressing and my diabetes is still very very kind and nice to me.

       

      I know two medical doctors who warn their patients to limit their intake of sweet fruits. I eat a lot of fruits 3x/day, and I always make sure that I eat them ahead of everything else.

       

      It is often said that as a type 2 diabetic ages, his pancreas' ability to produce insulin diminishes. The way I see it, any cell in my body will eventually phase out if it is getting irrelevant in the scheme of things. One way of saying it is, if you don't use it you lose it. I intentionally eat a lot of carbohydrates because they make the pancreas produce plenty of insulin. I make my pancreas work overtime 3x/day, believing that as I keep it very busy, it won't quit on me.

       

      The permission I asked for is not for me to quote you. I prefer sharing with other type 2s every word that you and I used. In fact, I want them to join in our conversations. You, being an expert on type 2 diabetes and a very well known author of many many books on diabetes, will surely be a good source of excellent information, ideas, and encouragements for all of us.

       

      Thank you very much.

       

      Bonny Damocles