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A1c Accuracy

Gretchen Becker
Gretchen Becker
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Author, Humorist, wildlyfluctuating.blogspot.com

Gretchen Becker studied biology for 8 years at Radcliffe/Harvard,...

Gretchen Becker

Saturday, March 21, 2009
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The hemoglobin A1c test, usually referred to simply as the "A1c," can be accurately translated into our average blood glucose (BG) levels for the past three months or so, right? Wrong. On average, you can produce formulas that estimate the average BG levels for the average patient, but these formul...
  1. mySpace, myDiabetesCentral.com, and myHgBA1C?!
    frankenduf
    Monday, March 23, 2009 at 05:05 PM

    while this is a good critique of the A1C, i feel it is somewhat of a smokescreen, in that trending A1C is always more important than a single (perhaps theoretically irreducible) measurement- in fact, one could critique any lab value along these lines, but it doesn't make the values invalid or inaccurate even if they deviate from the population norm- so trending A1C movement for an individual can be accurate even if it is varying from what is 'normal'- as Aristotle said, there is no science of the particular- but change in a particular can become a science- so i would integrate HgBA1C trend along with changes in weight, diet , and exercise as key pieces to modifying a diabetes plan of action, even if those pieces may be exotic

    Reply
    re: mySpace, myDiabetesCentral.com, and myHgBA1C?!
    Gretchen Becker
    Monday, March 23, 2009 at 08:45 PM

    Frank, I'm afraid I don't follow your logic. I agree that A1c trends in an individual are more important than absolute numbers -- within reason. Keeping your A1c at 13 is not a great idea even if it's not increasing, and I always advise people not to compare their A1c with someone else's but to look for trends instead.

     

    Nevertheless, many people want to know why their A1c doesn't jibe with their meter readings. And many physicians seem to accept the A1c-to-average-BG formulas. Hence I wanted people to understand that these formulas don't apply to everyone so they'd be able to discuss this with their doctor.

    Reply
  2. Gestational Diabetes
    Nicky
    Wednesday, March 25, 2009 at 12:55 PM

    My Granddaughter was treated for Gestational Diabetes, and 2 months after safely delivering a 1 month premie, (due to an amniotic fluid leakage that put the baby in jeopardy) we found out that she had been bleeding internally as a result of undiagnosed Chrones Disease! 

    During her pregnancy, even while taking the best vitamin protocol, she was anemic, iron deficient and feeling less than her normal healthy & bubbly self.

    After 2 months of steroid treatment and terrible weight loss she has had surgery, .  The outcome was better than any of us had even dared to hope and her surgeon suggested that she could safely complete another pregnancy after recovering.

    She is doing well now, her baby is a healthy 9 month old, and she is preparing to get pregnant again soon, as her Gastrointerologist says the sooner the better, if she wants another child.

    Is it possible that she really didn't have Gestational Diabetes? Would it be helpful to add this information to the mix, or would it be better to just let her be treated for Gestational Diabetes in the event that comes up again? 

    Reply
    re: Gestational Diabetes
    Gretchen Becker
    Wednesday, March 25, 2009 at 01:40 PM

    "Is it possible that she really didn't have Gestational Diabetes? Would it be helpful to add this information to the mix, or would it be better to just let her be treated for Gestational Diabetes in the event that comes up again?"

     

    According to that article, yes, it's possible she didn't have GDM. If it were me, I'd print out a copy of that article on GDM and show it to her doctor and ask his opinion.

     

    Assuming she learned how to measure BG in the last pregnancy, I think the best approach would be to carefully monitor her BGs in this one, just in case. I wouldn't "treat" it unless they were high, unless by "treat" you meant a careful diet. That's never a bad thing.

    Reply
  3. my a1c is lower than I think it really is because
    sammy
    Tuesday, July 07, 2009 at 05:46 PM

    My child has had higher sugars in three months...but she diets and fasts before going in to the doctor thus faking overall resuts!??

    Reply
    re: my a1c is lower than I think it really is because
    Gretchen Becker
    Wednesday, July 08, 2009 at 06:17 PM

    If your child is a teenager, I think such behavior is not uncommon. Some teens write fake numbers in their log books. The A1c was supposed to control for that, but having a lot of lows can cancel out a lot of highs, and because the A1c is heavily weighted toward recent weeks, very strict control for a couple of weeks would give inaccurate assessment of her control over the past few months.

     

    Teenagers think the future will never come. I sure did. As she gains maturity, such behavior should change and she'll realize that "cheating" with her BG results is only harming her.

    Reply
  4. A1C and Thalassemia
    Nicoletti
    Sunday, September 13, 2009 at 06:00 PM

    Hi Gretchen,

     

    I have thalassemia and last month was dx'ed as T2 diabetes. I'm having an A1C test next week, though I've read that because of the thalassemia, the results may not be accurately translated into my average blood glucose levels for the past three months.Is there another test that can be done that can?

     

    Thanks,

    Nicole

    Reply
    re: A1C and Thalassemia
    Gretchen Becker
    Sunday, September 13, 2009 at 08:42 PM

    Yes. Ask for the fructosamine test. This isn't used much, but it measures the glycation of albumin rather than hemoglobin.

    Reply
    re: re: A1C and Thalassemia
    Nicoletti
    Tuesday, September 15, 2009 at 04:40 PM

    Thanks, Gretchen, I will ask for that. Can I trust the readings I am getting at home from my glucose monitor?

    Reply
    re: re: re: A1C and Thalassemia
    Gretchen Becker
    Wednesday, September 16, 2009 at 08:17 AM

    I don't see why not. You're measuring glucose, not hemoglobin.

    Reply
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