Sunday, February 12, 2012

Metformin and Cancer

Normal 0 Many people see prescription drugs as a last resort. And there's some basis for this caution: most drugs have side effects, ranging from annoying to fatal.   However, not treating diseases also has side effects ranging from annoying to fatal. For example, we know that high blood ...
9/16/09 4:38pm
don't forget that metformin can lead to lactic acidosis, especially with kidney problems/old age and overdoses- metformin is now the non-insulin drug of first treatment (and/or sulfonylurea), with good reason: insulin sensitizing while helping to lose weight- my advice is to use it as treatment early in type 2, (unless contraindicated), and not to go over 2000mg/ day (diminishing marginal effects with higher doses)- routine kidney function tests as well (especially if hypertension)
9/16/09 6:28pm

They've found that lactic acidosis is much less common than they thought. And the dosages for cancer treatment (with doxorubicin) are much lower than those used for BG control.

Anonymous
Gaelyne
9/18/09 10:26am

Hi Gretchen!

 

I've been on Metformin for the last year and it really has helped keep my glucose under control, although I've also done my best to limit carbs and to exercise as well.

 

I was reading elsewhere about the metformin studies regarding cancer and noted that they used breast cancer cells in their testing. As an 8yr survivor of BC and a Type 2 Diabetic on Metformin, I really hope that the studies prove that it does stop cancer cells from developing. From my point of view, it would make being diagnosed as a T2 as a blessing of sorts. I'd rather live with diabetes than die early from BC.

9/18/09 10:45am

Glad you're doing well. I agree that in some ways, a diabetes diagnosis is a blessing in disguise as it forces us to live in a healthier way.

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