Children,Teens and Continuous Glucose Monitoring

By Dr. Fran Cogen, Health Pro Tuesday, November 02, 2010

Fellow blogger, Dr. Bill Quick, recently commented on his experiences with the continuous blood glucose monitoring system. He described the four systems that are currently available. Technology is an outstanding adjunct to improving diabetes self-care skills. However, in terms of quality of life (especially in young children and teens), when is it justified to add another layer of complexity to diabetes management? The American Association of Clinical Endocrinologists (AACE) recently published a Consensus Statement on Continuous Blood Glucose monitoring. The task force authors included diabetes specialists in all related subspecialties including pediatrics. The task force based its recommendations on a summary of randomized, controlled clinical trials using CGMS in type 1 diabetes patients. The studies include: STAR-1 for adults and adolescents greater than 12 years of age, JDRF for adults and teens greater than or equal to 15 years, DirecNet and JDRF CGM for children 8 to 14 years. These studies revealed an important consideration for children and adolescents. Children and teens were much less likely than adults to use CGM devices on a near-daily basis and the best results in the lowering of hb A1c were noted in those study participants who used the sensors 6 to 7 days per week. Another key finding was that pediatric patients who successfully lowered their hb A1c in the JDRF trials did so without increasing the amount of severe hypoglycemia. Indeed, the rates of severe hypoglycemia in the randomized trials were lower in pediatric patients in both the SMBG and personal CGM groups compared with previously reported data for intensively treated adolescents in the Diabetes Control and Complications Trial.

 

Overall Patient selection recommendations include:

  1. T1DM persons characterized by hypoglycemic unawareness or frequent hypoglycemia.
  2. Hb A1c above the target range with marked glycemic variability (major glucose fluctuations) that are judged to be very serious and life threatening.
  3. Persons with T1DM that need to lower hb A1c without increasing hypoglycemia.
  4. Preconception and pregnancy in women with T1DM.
  5. Children and adolescents with T1DM with hb A1c of less than 7.0.
  6. Children and adolescents with T1DM with hb A1c levels of 7.0 percent or higher who are able to use the device on a near-daily basis.
  7. Other children and adolescents considered to be good candidates for personal CGM along with a 2 to 4 week trial period include:
    1. Children and teens who monitor blood sugars frequently.
    2. Committed families of young children (younger than 8 years) especially if the child is having issues with hypoglycemia.
  8. Intermittent use of professional CGM in children and teens with T1DM may be useful for those undergoing changes to their diabetes regimen or are having problems with the following:
    1. Nocturnal hypoglycemia or the dawn phenomenon.
    2. Hypoglycemia unawareness.
    3. Postprandial hyperglycemia.

 

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By Dr. Fran Cogen, Health Pro— Last Modified: 12/14/10, First Published: 11/02/10