Prior to 2001, there were only three basal insulins that were used in combination with either regular or rapid acting insulin. NPH and Lente were intermediate acting insulin (duration 10-12 hours) along with Ultralente (duration 24-36 hours). These basal insulins had peaks that could increase the ris...


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Another problem with ultra-long-acting would be that if you injected too much, you'd be fighting lows for 3 days instead of 12 to 24 hours.
Oh 3 days of low bg... shoot me!
Absolutely! (rather obvious, isn't it?)