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Kim-   Hello! before I started using insulin, I was on glipizide and medtformin. They worked great for me but when my pancreas stopped producing, I was switched to insulin 24/7; I am Type 1.5/LADA.   There are a few things about diabetic med's.  What works for others may not work for you.  When you go to your next appointment make time to talk to your physician about the different medications that are on the market that may be beneficial to you. We all are fighting diabetes but our bodies react differently to treatment.  You mention that your medication isn't working...have you changed your diet? when was the last time you had labs done? you may need to have some done if nothing has changed. This best answer is to talk to your physician.     Cherise Community Moderator