FROM OUR EXPERTS

  • Ann Bartlett
    Health Guide
    October 16, 2008
    Ann Bartlett
    Health Guide
    October 16, 2008

    I'm not in favor of a quick yes to this answer for you.  To begin you need to understand the honeymoon phase.  After initial diagnosis and treatment there is a period of recovery for the beta cells. As a result the remaining beta cells may be able to produce enough insulin to keep blood sugars relatively stable for weeks, months and even years.  Eventually beta cell function ceases and the insulin requirements go up.  So diet isn't the be all end all in stabilizing the beta cell function.  

     

    There is a company called Macrogenics that is running trials for a protocol that looks to hold honeymoon periods and has reversed some cases of diabetes in very young children.  The best place for you, your parents  and your endocrinologist to decide what might be an option for you go to JDRF and scroll through research to clinical trials.  You could be a real candidate!  

     

    Besides that exercise, eating well and understanding low carb dieting is very important information so you know how to take proper care of your whole body! 

     

    Have you checked out diabeteens?  Lots of teens and college age kids talking about life with diabetes.  Ask your question to the expert: Dr. Cogan.  She's great, I know her very well and she would answer you with lots of information and honesty!

     

    I'm very impressed!  You're asking all the right questions right from the start!

    Keep us "posted" on how you are doing!

     

    Best,

    Ann Bartlett

    • kathy doura
      February 27, 2010
      kathy doura
      February 27, 2010

      Hi, Ann

       

      I'm really impressed by you as mother; I read your article just yesterday and i learned that you have a son with type 1 diabetes and your concerned about your other two sons.

      As matter fact my son 4 years old and 11 months just got diagnosed a month ago with type 1 diabetes, i was told by the doctor that he is still in his honey moon period.

      I'm very confused i don't know what to do as mother and i'm pregnant in my second trimester with the second child.

      I will do what ever a takes to at least try to prolong his honey moon period.

      Since you have knowledge than i do, so please I'm asking for your help if you can email me.

       

       

      THANK YOU

      READ MORE
    Click here to login before answering a question
  • Dr. Fran Cogen
    Health Pro
    February 27, 2010
    Dr. Fran Cogen
    Health Pro
    February 27, 2010

    Hi there: I am writing back to you after 2 of our fellow healthcentral bloggers: Ann and Beth, referred your question to me. I am Dr. Cogen, the type 1 diabetes expert for mydiabetescentral.com. Firstly, I am in agreement with Ann in regard to her previous post including consideration of the Protege trial if your child fits the criteria: age and weight are important factors. Secondly, for further information on The Honeymoon period, I would like you to take the opportunity to read one  of my recent blogs about the HP. In answer to your question if the honeymoon period can be prolonged by following a low carb diet, I have several comments. The honeymoon period can be prolonged by giving exogenous insulin by injections in order to "destressify" (my made- up word) your child's remaining living islet cells. By providing a low carb diet, in theory, the islet cells would perhaps be required to puff out less "bolus insulin" in a sense. However, adolescents require a balanced diet of carbohydrates (preferably complex), protein, fat etc. To eat ONLY a low carb diet would be difficult in terms of pubertal/growth needs/sports requirements etc. as well as adherence. (It would be really tough for a 16 year to follow such a strict diet, let alone follow all the diabetes self care skills your diabetes team suggests.) We, at Children's National Medical Center, do not routinely recommend our children and teens to follow a low-carb diet while in the honeymoon or thereafter because of the unique needs of growing children and adolescents. I hope this information is helpful.

     

    Best of luck,

    DrC

    • pgy
      pgy
      April 07, 2011
      pgy
      pgy
      April 07, 2011

      Dear Dr Fran

       

      I understand there are some research trials looking at very tight control of BGLs at time of diagnoses to prolong the honeymoon period.

       

      Can you comment please.

      READ MORE
    • Dr. Fran Cogen
      April 09, 2011
      Dr. Fran Cogen
      Health Pro
      April 09, 2011

      Good evening: The research trials of which I am familiar include the Diamyd (GAD-65 antibody vaccine), PROTEGE /DEFEND trials (monoclonal antibody trials)and Antrypsin antibody trials. I do not specifically know about trials that involve tight control of blood sugars at diagnosis to prolong the honeymoon period. However, most diabetes teams work to try to get everyone in tight control immediately after diagnosis, regardless of whether or not someone is in the honeymoon period. If you know of specific trials, please let me know. I personally try to keep everyone's blood sugars within the tightest range possible in order to not only keep the beta cells puffing out insulin but to avoid future complications. Hope this is helpful.

      Dr.Cogen

      READ MORE
    • pgy
      pgy
      April 09, 2011
      pgy
      pgy
      April 09, 2011

      http://clinicaltrials.gov/ct2/show/NCT00891995?term=tight+blood+glucose+control+AND+progression&rank=1

      READ MORE
    • Dr. Fran Cogen
      April 11, 2011
      Dr. Fran Cogen
      Health Pro
      April 11, 2011

      I have reviewed the clinical trial and noted that there are 2 arms of the trial:

      1. closed loop treatment in a hospital setting with intensive insulin management followed up with the insulin pump and cgm in the outpatient setting

      2. standard therapy with insulin and routine glucose monitoring by glucometer. I have found no mention using a low carb diet in conjunction with the 2 interventions.

      The primary outcome is to see if intensive insulin therapy can prolong the life of the beta cells (nothing to do with low carb diet). I hope this answers your query.

      DrCogen

      READ MORE
    Click here to login before answering a question

FROM OUR COMMUNITY

You should know Answers to your question are meant to provide general health information but should not replace medical advice you receive from a doctor. No answers should be viewed as a diagnosis or recommended treatment for a condition. Content posted by community members does not necessarily reflect the views of Remedy Health Media, which also reserves the right to remove material deemed inappropriate.