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Adjusting insulin doses when traveling across time zones can be tricky. How to do it depends on several factors: what insulin you are using, when meals will be eaten, whether you can get any exercise during the flight, and even whether you're flying west to east, or east to west.   For people who are on an insulin pump, or using mealtime boluses of insulin and a daily basal shot of Lantus, it's really pretty easy. Just stay on the basal dose at the same time as you would take it at your home time zone, and take your mealtime boluses whenever you eat.   On the other hand, for folks who are using a premix like 70/30 twice daily, or a single bedtime shot of NPH, or other programs, it's impossible for me to generalize an answer: speak to your diabetes nurse educator or diabetes doc to work out something that will work for you.   And a final hint for everyone taking insulin and traveling: be sure to check zillions of blood sugars to see how things are going -- due to changes in your meal times, exercise pattern, and sleep cycles, things will inevitably get a little screwy, and checking your blood sugar and knowing how to make adjustments is critical.   Hope this helps!