Will taking anti-reflux drugs make you deficient in vitamin B 12 ? A recent article suggests that they could.
According to this research, patients who took PPIs (proton pump inhibitors) for more than 2 years had a 65% increase in vitamin B 12 deficiency. The H 2 inhibitors (for example, ranitidine [Zantac]) also increase risk but not as much as the PPIs.
This sounds scary. Vitamin B 12 deficiency can be serious.
But don’t panic and throw-out your antireflux drugs without investigating further.
They’re using a type of statistics that can magnify a small effect. For example, let’s say the risk of something in your age group is 2%. You have a 65% increased risk. That means your risk is 3.3%. Greater, yes, but still relatively low.
Metformin can also contribute to vitamin B 12 deficiency. This has been known since before I was diagnosed in 1996. In fact, the effect of the PPIs on B 12 deficiency has also been known for some time, as mentioned i...
Could a combination of the vitamins B12, B6 and folic acid be first effective “drug” to slow down the progression of Alzheimer’s disease? The concept looks promising. The Proceedings of the National Academy of Sciences recently published information about a study on aging volunteers that has demonstrated how this combination of B vitamins has, in their trials, slowed atrophy of gray matter in brain areas affected by Alzheimer’s disease. In the words of senior study author A. David Smith, professor emeritus of pharmacology at Oxford University in England, “It’s a big effect, much bigger than we would have dreamt of.”
According to an article on BloombergBusinessweek.com, volunteers for the PNAS study were given either a placebo or a combination of 0.5 milligrams of vitamin B12, 20 milligrams of vitamin B6 and 0.8 milligrams of folic acid. At the start of the trial, the participant’s brains were scanned using magnetic-resonance imagi...
Generic Name: VITAMIN B COMPLEX - ORAL B Complex-Vitamin B12 Oral Precautions
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If you have any of the following health problems, consult
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vitamin B12 deficiency (pernicious anemia)
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