I recently received an interesting question (which I paraphrase below): Nondiabetics' mean blood sugar level is around 83 mg/dl, whereas our teachers and the ADA recommend keeping it between 80 to 120 mg/dl. This is allowing patients to leave it >30% higher than where they could have been with better control. Is this not the reason of having a lot of vascular and neurological complications? Are the advisors giving loose and harmful advice? Is there a way to have a real fact and clinical study to base the advice for the benefit of people afflicted with diabetes? My answer: The concern about targeting normal values for blood glucose and A1C in people with diabetes has always been the issue of provoking hypoglycemia if aiming for normal values. Recently, there's been an additional concern identified when aiming for perfection: In patients with T2DM plus cardiovascular disease (or cardiovascular risk), aiming for lower values of A1C (below 6) increased the risk of death compared to aiming fo...
I recently saw the following question:
My granddaughter’s HgbA1c was elevated to 10. Her glucose readings have been normal. Why does she have this elevated reading?
It seems obvious at first glance that either the elevated HgbA1c is wrong, or the glucose readings are misleading. I’ll assume that your granddaughter has a diagnosis of diabetes, and that the glucose readings you describe are being done by her with a home glucose meter, rather than being done in a commercial laboratory. You don’t describe her as being a child, teen, or adult, but the issues are mostly age-independent.
As you are aware, the glycosylated hemoglobin test (called by various acronyms including HgbA1c and A1C) has a normal range well below your granddaughter’s value of 10. In people without diabetes, the value is usually about 5; for people with diabetes, most endocrinologists would want to see the value below 7. So, based on her value of 10, one would assum...
HbA1c is a test that measures the amount of glycated hemoglobin in your blood. Your doctor may order this test if you have diabetes.
Glycated hemoglobin; Glycosylated hemoglobin; Hemoglobin - glycosylated; A1C; GHb; Glycohemoglobin; Diabetic control index
How the test is performed
Blood is drawn from a vein. The vein is usually on the inside of your elbow or the back of your hand. A nurse will clean the site for germs. The nurse then wraps an elastic band around the upper arm. This puts pressure on the area and makes the vein swell with blood.
Next, the needle is gently inserted into your vein. The blood collects into an airtight vial or tube attached to the needle. The elastic band is removed from your arm. Once the blood has been collected, the needle is removed. Then the area is covered to stop any bleeding.
In infants or young children, a sharp tool called a lancet may be used to puncture the skin and make it ble...
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