Reprinted with permission from Amy Tenderich of www.diabetesmine.com . Another larger-than-life Diabetes Marketing War , this time without the romantic names: I wrote a post introducing the first-ever competitor to Sanofi-Aventis' long-acting insulin, Lantus. The new product is called Levemir , from Novo Nordisk. What I missed more recently was that things turned ugly back in March. Sanofi filed suit against Novo Nordisk in a New Jersey U.S. District Court claiming that Novo was falsely promoting their drug as effective for 24 hours, which Sanofi claims is not true. The case was dropped on June 23 for lack of evidence, so Novo can go on making its long-lasting efficacy claim. Who's right here? Who knows? Novo's studies do seem to confirm its other two points of differentiation: that Levemir is well-absorbed by patients and causes less weight gain. Meanwhile a report released at the recent ADA Conference shows that a once-a-day dose of Lantus and Levemir have similar effects ...
Insulin nomenclature is clearly confusing. Among other reasons:
The same product may have several different names; the names may be different in the U.S. compared to other countries; the same product may be made by several manufacturers and given differing names.
The product may be from different sources (previously all insulin came from animal pancreases: beef, pork, or mixed beef/pork; but now-a-days, insulins usually are semisynthetic human).
Insulins are classified by duration of action, as being rapid, intermediate, and prolonged.
Several manufacturers may also mix two insulin products into the same vial, producing mixtures of 70% one and 30% another, or 50/50. To make it worse, what the US calls 70/30 would be called 30/70 in Europe! And in the US, 70/30, 75/25, and 50/50 are the usual mixtures, but in Europe there will be others such as 80/20 (oops, 20/80).
Some of the "big players" in the insulin arena are described below. I give the U.S. brand name first, then common na...
Generic Name: INSULIN DETEMIR - INJECTION Pronounced: (IN-sue-lin DET-a-meer) Levemir SubQ Overdose
If overdose is suspected, contact your local poison
control center or emergency room immediately. US residents can call the US
national poison hotline at 1-800-222-1222. Canadian residents should call their
local poison control center directly. Symptoms of overdose may include
headache, sweating, shakiness, increased hunger, vision changes, nervousness,
tiredness, seizures, loss of consciousness.
Levemir SubQ Missed Dose
It is very important to follow your insulin regimen
exactly. Do not miss any doses of insulin. Discuss specific instructions with
your doctor now in case you miss a dose of insulin in the
Levemir SubQ Notes
Do not share this medication, needles, or syringes with
It is recommended you attend a diabetes education program
to understand diabetes and all the important aspects of its treatment,
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