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Hi sunantr,   Thank you for your question. The use of glucosamine and chondroitin in diabetics is controversial. Some reports argue that the glucosamine can raise glucose levels, while other reports claim that there is no effect. If you look at this page from the Mayo Clinic, there is some information about glucosamine. It specifically says this about use in diabetics:   "It remains unclear if glucosamine alters blood sugar levels. Several human studies suggest that glucosamine taken by mouth has no effects on blood sugar, while other research reports mixed effects on insulin. When glucosamine is injected, it appears to cause insulin resistance and endothelial dysfunction. Preliminary studies show no effect on mean hemoglobin A1c concentrations in patients with type 2 diabetes mellitus. Caution is advised in patients with diabetes or hypoglycemia and in those taking drugs, herbs, or supplements that affect blood sugar. Serum glucose levels may need to be monitored by a healthcare provider and medication adjustments may be necessary."   I would recommend that you talk to your father's physician and ask what he or she recommends. Best of luck!   Casey