Wednesday, October 22, 2014

Saturday, September 20, 2008 Simms14, Community Member, asks

Q: Should I take Actos for prediabetes?

Should I go on Actos for prediabetes?  My blood surgar was 110 on a recent blood test after I have lost 10 pounds and have been on an excercise program before even becoming aware that I have prediabetes.  My doctor thought I should go on Actos.  Is this something that should be done as a way of preventing type 2 diabetes? 

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Answers (3)
Dr. Bill Quick, Health Pro
4/ 6/12 9:12am


Please see my discussion, Questions about prediabetes

Hope this helps!


William W. Quick, MD, FACP, FACE

Editor, D-is-for-Diabetes

frankenduf, Community Member
9/22/08 4:26pm

2 questions: 1- should you take a drug to prevent DM

                  2- which drug

1: If you have another risk factor, and are trending higher, then I would recommend trying a drug.  Risk factors include a family history of DM, and/or a high sugar after you eat a meal, i.e. over 140 2 hours after.  And since you are losing weight, you could wait @ 3 months and recheck fasting sugar- if trending down, I would hold off on a drug.

2: If you are at higher risk and trending up, drugs can prevent DM (although can cause other problems...).   If you are relatively young (<40) and very heavy (BMI > 36), I would recommend metformin, unless liver or kidney problems.  If you are not so overweight, actos is good as well, unless you have congestive heart failure.  The difference is that metformin will help you lose weight, but actos does not.


Overall, actos can help prevent diabetes, but like any drug can cause other problems.  You sound like you are a good patient, so keep up with the diet and exercise.  I would only use a drug if you are doing 'the right stuff', but your numbers don't improve.  Best of luck and remember- we're all prediabetic if we live long enough :)

Rosy, Community Member
6/ 9/10 10:15am


Actos (Pioglitazone) is used to treat type 2 diabetes by reducing the resistance your body has to insulin.


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Stop using Actos and get emergency medical help if you have any of these signs of an allergic reaction: (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); nausea, vomiting, abdominal pain, or loss of appetite; unusual fatigue; yellowing of the skin or eyes; or dark urine.


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By Simms14, Community Member— Last Modified: 05/19/14, First Published: 09/20/08