A recent report again reaffirms that metformin is the first medication to use when a patient with type 2 diabetes (T2D) needs help with lowering blood glucose levels. The 200+ page report, Oral Diabetes Medications for Adults With Type 2 Diabetes: An Update , was prepared for the Agency for Healthcare Research and Quality by the Johns Hopkins University Evidence-based Practice Center. It is loaded with tables and discussions, but the conclusion is strikingly brief: "Although the long-term benefits and harms of diabetes medications remain unclear, the evidence supports use of metformin as a firstline agent. Comparisons of two-drug combinations showed little to no difference in HbA1c reduction, but some combinations increased risk for hypoglycemia and other adverse events."
To summarize the findings from the report: An older diabetes drug, metformin, works better, and has fewer side effects than newer drugs for T2D. It's also cheaper, as it's been available as a generic for y...
Generic Name: GLIPIZIDE/METFORMIN - ORAL Pronounced: (GLIP-eh-zide/met-FOR-min) Glipizide-Metformin Oral Overdose
If overdose is suspected, contact your local poison
control center or emergency room immediately. US residents can call the US
National Poison Hotline at 1-800-222-1222. Canada residents can call a
provincial poison control center. Overdose can cause lactic acidosis and low
blood sugar. Symptoms of overdose may include: rapid breathing, severe
drowsiness, slow/irregular heartbeat.
Glipizide-Metformin Oral Missed Dose
If you miss a dose, take it as soon as you remember. If it
is near the time of the next dose, skip the missed dose and resume your usual
dosing schedule. Do not double the dose to catch up.
Glipizide-Metformin Oral Notes
Do not share this medication with others.
You should attend a diabetes education program to learn
more about diabetes and all the important aspects of its treatment, including
Q. I’ve just been diagnosed with lymphedema. What are the treatments like? A. Depending on the seriousness of your case, treatments can range from a simple hand massage, exercises, and instructions to keep your arm elevated for a portion of each day; to daily hours-long treatments for several weeks, followed by wearing a wrist to shoulder elastic sleeve, potentially for life. In other words: HUGE possible range of treatments. You won’t know what YOUR treatment will be like till you see the physical therapist or lymphedema therapist for the first time. However, you can hazard a guess, based on how much swelling you see and feel in your arm/chest area: the greater the swelling, the more advanced the lymphedema probably is, the longer-lasting the treatment will be. Q. So, let’s take a middle-of-the-road scenario, just as an example. What might that look like? A. At your first visit, the PT will measure both arms very carefully, taking their circumference ...
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