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Friday, January 21, 2011 Suz, Community Member, asks

Q: Does Splenda or any other articial sweetner raise your blood sugar as same as plain old sugar?

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Answers (3)
verdungal, Community Member
1/24/11 12:40pm

Artificial sweeteners don't affect your blood sugar level. In fact, most artificial sweeteners are considered "free foods" because they are not macronutrients.i.e. carbohydrates, protein or fat.

 

Effect of the artificial sweetener, sucralose, on gastric emptying and incretin hormone release in healthy subjects.Ma J, Bellon M, Wishart JM, Young R, Blackshaw LA, Jones KL, Horowitz M, Rayner CK.
University of Adelaide, Discipline of Medicine, Royal Adelaide Hospital, North Terr., Adelaide SA 5000, Australia.

The incretin hormones, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), play an important role in glucose homeostasis in both health and diabetes.

 

In mice, sucralose, an artificial sweetener, stimulates GLP-1 release via sweet taste receptors on enteroendocrine cells. We studied blood glucose, plasma levels of insulin, GLP-1, and GIP, and gastric emptying (by a breath test) in 7 healthy humans after intragastric infusions of 1) 50 g sucrose in water to a total volume of 500 ml (approximately 290 mosmol/l), 2) 80 mg sucralose in 500 ml normal saline (approximately 300 mosmol/l, 0.4 mM sucralose), 3) 800 mg sucralose in 500 ml normal saline (approximately 300 mosmol/l, 4 mM sucralose), and 4) 500 ml normal saline (approximately 300 mosmol/l), all labeled with 150 mg 13C-acetate.

 

Blood glucose increased only in response to sucrose (P<0.05). GLP-1, GIP, and insulin also increased after sucrose (P=0.0001) but not after either load of sucralose or saline. Gastric emptying of sucrose was slower than that of saline (t50: 87.4+/-4.1 min vs. 74.7+/-3.2 min, P<0.005), whereas there were no differences in t50 between sucralose 0.4 mM (73.7+/-3.1 min) or 4 mM (76.7+/-3.1 min) and saline.

 

We conclude that sucralose, delivered by intragastric infusion, does not stimulate insulin, GLP-1, or GIP release or slow gastric emptying in healthy humans.

 

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Erica, Community Member
1/23/11 12:17pm

Artificial sweeteners are not suppose to be able to raise blood sugar and should not do so unless you are eating mass amounts of them (they do have a very small amount of carbs in some forms (dry powder mainly)).  However, they can trick your body into thinking you are eating something sweet thereby increasing your insulin output and therefore cause you to want to eat.  If you are finding you are having an increase in blood sugar after eating or drinking them, and there is no other carbohydrates in the food/beverage, then it could be from an allergy or sensativity to them.

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rosey1234, Community Member
1/23/12 2:25pm

noSmile

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By Suz, Community Member— Last Modified: 01/23/12, First Published: 01/21/11