A few days ago I was browsing through an old physiology textbook, the one I used when I was in college, because I was curious to read what they said about diabetes way back then.
The book, Textbook of Medical Physiology, second edition, by Arthur Guyton, was copyright in 1956, more than 50 years ago. And I came across this statement:
"In the early days of treating diabetes it was the tendency to reduce the carbohydrates in the diet so that the insulin requirements would be minimized. This procedure kept the blood sugar level down to normal values and prevented the loss of glucose in the urine, but it did not prevent the abnormalities of fat metabolism. Actually, it exacerbated these. Consequently, there is a tendency at present to allow the patient a normal carbohydrate diet and then to give simultaneously large quantities of insulin to metabolize the carbohydrates. This depresses the rate of fat metabolism and also depresses the high level of blood cholesterol which occurs in diabete...
Everybody does it...or at least that's what I told myself. I'd gotten away with doing it for several months: purposefully letting my blood sugars run high because I hate having lows . I'd developed this bad habit one year ago, during a summer where I was filling all of my free time with mile-long runs to the gym where I'd spend at least an hour weight lifting, taking yoga classes three times a week and jiu-jitsu classes twice a week. That all sounds dandy for a healthy diabetic, but the problem was that I was trying so hard to never go low that I was far too often running a regular 200+ blood sugar. We all know a low blood sugar in the middle of a run or a jiu-jitsu class basically puts a big RED LIGHT on the activity. My other issue was that jiu-jitsu classes were so intense that I was worried I wouldn't be able to feel the low blood sugar symptoms until it was too late, so I compensated in the most unhealthily way: a decent-sized bowl ...
Normally, there are no antibodies against insulin in your blood.
Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.
What abnormal results mean
If you have IgG and IgM antibodies against insulin, your body reacts as if the insulin is foreign. This may make insulin less effective, or not effective at all.
The antibodies can also change the amount of time it takes insulin to work, putting you at risk for low blood sugar. This means that the insulin cannot move glucose from the bloodstream into the cells. As a result, increased levels of insulin are needed to have the same effect, which is called insulin resistance.
If the test shows high levels of IgE antibody against insulin, your body has developed an allergic response to the medication. This could put you at risk for skin reactions, or more severe reactions. Other medications, such as antihistamines or low-dose i...
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