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Monday, July 7, 2008

Prandin Oral

Drug Interactions


Generic Name: REPAGLINIDE - ORAL
Pronounced: (reh-PAGG-lin-ide)

Prandin Oral Interactions

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious interactions may occur:

  • gemfibrozil
  • gatifloxacin


If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting repaglinide.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

  • azole antifungals (e.g., itraconazole, ketoconazole)
  • erythromycin
  • clarithromycin
  • cyclosporine
  • protease inhibitors (e.g., ritonavir, saquinavir)
  • rifampin
  • carbamazepine
  • nonsteroidal anti-inflammatory drugs (e.g., ibuprofen, naproxen)
  • aspirin and aspirin-like drugs (e.g., salsalate)
  • sulfa drugs (e.g., sulfamethoxazole, glipizide, glyburide)
  • probenecid
  • chlorambucil
  • trimethoprim or trimethoprim/sulfamethoxazole
  • warfarin
  • MAO inhibitors (e.g., phenelzine)
  • certain cholesterol-lowering drugs (e.g., simvastatin)


Some drugs may affect your blood sugar levels and make control of your blood sugar more difficult. If you start or stop these medications while taking repaglinide, you should check your blood sugar levels more frequently. Tell your doctor or pharmacist if you are taking any of these medications/herbal products:

  • certain water pills (e.g., furosemide, hydrochlorothiazide)
  • oral corticosteroids (e.g., prednisone, dexamethasone, prednisolone)
  • phenothiazines (e.g., chlorpromazine, trifluoperazine)
  • newer drugs for mental/mood problems (e.g., olanzapine, clozapine, risperidone, ziprasidone)
  • birth control pills
  • estrogens
  • niacin
  • sympathomimetics (e.g., pseudoephedrine)
  • isoniazid
  • thyroid drugs
  • some calcium channel blockers (e.g., nifedipine)
  • fenugreek
  • ginseng
  • gymnema
  • alcohol
  • quinolone antibiotics (e.g., ciprofloxacin, levofloxacin)
  • some protease inhibitors (e.g., indinavir, amprenavir)
  • somatropin
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