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Monday, July 7, 2008

Glynase Oral

Drug Interactions


Generic Name: GLYBURIDE - ORAL
Pronounced: (GLY-byur-ide)

Glynase Oral Interactions

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medication because a very serious interaction may occur:

  • bosentan


If you are currently using this medication, tell your doctor or pharmacist before starting glyburide.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription products you may use, especially of:

  • other diabetes drugs (e.g., insulin, metformin)
  • aspirin or aspirin-like drugs (e.g., salicylates, NSAIDs such as ibuprofen, phenylbutazone)
  • azole antifungals (e.g., fluconazole)
  • birth control pills
  • "blood thinners" (e.g., warfarin)
  • calcium channel blockers (e.g., diltiazem)
  • chloramphenicol
  • clofibrate
  • corticosteroids (e.g., prednisone)
  • decongestants (e.g., pseudoephedrine)
  • diazoxide
  • diet pills
  • epinephrine
  • estrogens
  • isoniazid
  • MAO inhibitors (e.g., furazolidone, linezolid, moclobemide, phenelzine procarbazine, selegiline, isocarboxazid, tranylcypromine)
  • niacin
  • phenothiazines (e.g., promethazine)
  • phenytoin
  • probenecid
  • quinolone antibiotics (e.g., ciprofloxacin)
  • rifampin
  • sulfonamides (e.g., sulfa antibiotics)
  • thyroid drugs
  • "water pills" (diuretics such as hydrochlorothiazide, furosemide)
  • fenugreek
  • ginseng


Beta-blocker medications (e.g., metoprolol, propranolol, glaucoma eye drops such as timolol) may prevent the fast/pounding heartbeat you would usually feel when your blood sugar level falls too low (hypoglycemia). Other symptoms of low blood sugar such as dizziness, hunger, or sweating are unaffected by these drugs.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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