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Monday, July 7, 2008

AVANDAMET Oral

Drug Interactions


Generic Name: ROSIGLITAZONE/METFORMIN - ORAL
Pronounced: (row-sih-GLIT-uh-zone/met-FOR-min)

AVANDAMET Oral Interactions

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

  • birth control pills
  • bupropion
  • calcium channel blockers (e.g., nifedipine)
  • cephalexin
  • cimetidine
  • corticosteroids (e.g., prednisone)
  • decongestants
  • other diabetes drugs (e.g., glyburide, acarbose, insulin)
  • estrogens
  • gemfibrozil
  • herbal products (e.g., fenugreek, Gymnema, ginseng)
  • isoniazid
  • niacin
  • phenothiazines (e.g., chlorpromazine)
  • phenytoin
  • nitrates (e.g., isosorbide dinitrate)
  • quinolone antibiotics (e.g., ciprofloxacin)
  • rifampin
  • thyroid drugs
  • "water pills" (diuretics such as hydrochlorothiazide, furosemide)


Beta-blocker medications (e.g., metoprolol, propranolol, glaucoma eye drops such as timolol) may prevent the fast/pounding heartbeat you would usually feel when your blood sugar level falls too low (hypoglycemia). Other symptoms of low blood sugar such as dizziness, hunger, or sweating are unaffected by these drugs.

If you are scheduled to undergo any X-ray or scanning procedure using injectable iodinated contrast material, be sure to inform your doctor that you are taking this medication. You will need to temporarily stop this medication around the time of your procedure. Consult your doctor for further instructions.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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