This combination medication is used along with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes (non-insulin-dependent diabetes). This medication works by helping to restore your body's proper response to the insulin you naturally produce.
You should only begin taking rosiglitazone/metformin when other drugs have not worked well or cannot be taken, and you do not wish to take pioglitazone-containing medications. If you are currently taking rosiglitazone/metformin and have good control of your blood sugars and no new side effects/symptoms, continue to take this medication as directed. Ask your doctor promptly about the risks and benefits of it, since a small number of people have had serious side effects (see Warning Section).
After November 18, 2011, only patients enrolled in the Avandia-Rosiglitazone Medicines Access Program may obtain and use rosiglitazone-containing products. Your doctor will need to register you with this program before you can receive your prescription. Only physicians enrolled in the Avandia-Rosiglitazone Medicines Access Program may prescribe rosiglitazone-containing products, and only certified mail-order pharmacies enrolled in the program may dispense them. Talk to your doctor or pharmacist for more details about the program.
Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Rosiglitazone belongs to a class of drugs known as thiazolidinediones or "glitazones." Metformin is a biguanide-type drug.